Protein Alignment CkIIalpha and CSNK2A1

DIOPT Version :10

• Sequence 1: NP_524918.1
• Gene: CkIIalpha / 48448
• FlyBaseID: FBgn0264492
• Length: 336
• Species: Drosophila melanogaster
• Sequence 2: NP_001886.1
• Gene: CSNK2A1 / 1457
• HGNCID: 2457
• Length: 391
• Species: Homo sapiens
• Alignment Length: 327
• Identity: 290/327 - (88%)
• Similarity: 309/327 - (94%)
• Gaps: 0/327 - (0%)

  Fly     3 LPSAARVYTDVNAHKPDEYWDYENYVVDWGNQDDYQLVRKLGRGKYSEVFEAINITTTEKCVVKI 67
            :||.||||||||.|:|.||||||::||:||||||||||||||||||||||||||||..||.||||
Human     5 VPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKI 69

  Fly    68 LKPVKKKKIKREIKILENLRGGTNIITLLAVVKDPVSRTPALIFEHVNNTDFKQLYQTLTDYEIR 132
            ||||||||||||||||||||||.|||||..:|||||||||||:|||||||||||||||||||:||
Human    70 LKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIR 134

  Fly   133 YYLFELLKALDYCHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLAEFYHPGQEYNVRVASRYFKG 197
            :|::|:|||||||||||||||||||||||||||:|||||||||||||||||||||||||||||||
Human   135 FYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKG 199

  Fly   198 PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEELYAYLDKYNID 262
            |||||||||||||||||||||||||||||||||||||||||||||||||||||:||.|:|||||:
Human   200 PELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIE 264

  Fly   263 LDPRFHDILQRHSRKRWERFVHSDNQHLVSPEALDFLDKLLRYDHVDRLTAREAMAHPYFLPIVN 327
            |||||:|||.|||||||||||||:|||||||||||||||||||||..||||||||.||||..:|.
Human   265 LDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 329

  Fly   328 GQ 329
            .|
Human   330 DQ 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CkIIalpha	NP_524918.1	STKc_CK2_alpha	18..322	CDD:271034	275/303 (91%)
CSNK2A1	NP_001886.1	STKc_CK2_alpha	20..325	CDD:271034	276/304 (91%)
		Interaction with beta subunit. /evidence=ECO:0000250	36..41		4/4 (100%)