Protein Alignment Acph-1 and ACP3

DIOPT Version :9

• Sequence 1: NP_733332.1
• Gene: Acph-1 / 48445
• FlyBaseID: FBgn0000032
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_001127666.1
• Gene: ACP3 / 55
• HGNCID: 125
• Length: 418
• Species: Homo sapiens
• Alignment Length: 408
• Identity: 147/408 - (36%)
• Similarity: 223/408 - (54%)
• Gaps: 42/408 - (10%)

  Fly    59 ATLPGQLKFVHVIYRHGDRTPVDPYPTDPWGDRKFWPTGWGDLTNLGKQEHYDLGKWLRNRYSNL 123
            :.|..:||||.:::|||||:|:|.:||||..:.. ||.|:|.||.||.::||:||:::|.||...
Human    29 SVLAKELKFVTLVFRHGDRSPIDTFPTDPIKESS-WPQGFGQLTQLGMEQHYELGEYIRKRYRKF 92

  Fly   124 LPPIYSNENIYVQSTDVDRTLMSAQSNLAGLYEPQGEDIWNTDINWQPIPIHTSPEREDPILAAK 188
            |...|.:|.:|::|||||||||||.:|||.|:.|:|..|||..:.|||||:||.|..||.:|...
Human    93 LNESYKHEQVYIRSTDVDRTLMSAMTNLAALFPPEGVSIWNPILLWQPIPVHTVPLSEDQLLYLP 157

  Fly   189 -APCPAYDYELASLES----SPEFKALTEKHRNLFAYLSEKGGRPVKTFIDAQYL-------NNT 241
             ..||.:.    .|||    |.||:.....:::..|.|.:..|      :..|.|       .:.
Human   158 FRNCPRFQ----ELESETLKSEEFQKRLHPYKDFIATLGKLSG------LHGQDLFGIWSKVYDP 212

  Fly   242 LFIENLYNMTLPKW------TKMVYGRE--ELTYVSNFAFAISSYTRKLARLKAGPLLKDIFQRF 298
            |:.|:::|.|||.|      ||:   ||  ||:.:|  .:.|.....| :||:.|.|:.:|....
Human   213 LYCESVHNFTLPSWATEDTMTKL---RELSELSLLS--LYGIHKQKEK-SRLQGGVLVNEILNHM 271

  Fly   299 KEKSSGSLKPDRSMWVYSAHDTTVASVLNALKLFELHSPPYTACIMMELRVDETNTPLVSIFYKN 363
            |..:  .:...:.:.:||||||||:.:..||.::....|||.:|.:.||.. |.....|.::|:|
Human   272 KRAT--QIPSYKKLIMYSAHDTTVSGLQMALDVYNGLLPPYASCHLTELYF-EKGEYFVEMYYRN 333

  Fly   364 TTA-EPLPLDIPGCGPSCPLTKLMNIYEDVLPVDWERECKLSTMMMTYEEANLGTATGILILIVI 427
            .|. ||.||.:|||.|||||.:...:...|:|.||..|| ::|......:.....|..::..:::
Human   334 ETQHEPYPLMLPGCSPSCPLERFAELVGPVIPQDWSTEC-MTTNSHQVLKVIFAVAFCLISAVLM 397

  Fly   428 ALLFASYGLMIYYRRRNY 445
            .|||......:.::|.:|
Human   398 VLLFIHIRRGLCWQRESY 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acph-1	NP_733332.1	HP_HAP_like	64..361	CDD:132717	118/316 (37%)
ACP3	NP_001127666.1	HP_HAP_like	34..332	CDD:132717	118/317 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165155677
Domainoid	1	1.000	163	1.000	Domainoid score	I3961
eggNOG	1	0.900	-	-		E1_KOG3720
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	239	1.000	Inparanoid score	I3355
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1221585at2759
OrthoFinder	1	1.000	-	-		FOG0002540
OrthoInspector	1	1.000	-	-		mtm8533
orthoMCL	1	0.900	-	-		OOG6_100295
Panther	1	1.100	-	-	O	PTHR11567
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R958
SonicParanoid	1	1.000	-	-		X1300
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	13	12.830