Protein Alignment Acph-1 and ACP6

DIOPT Version :10

• Sequence 1: NP_733332.1
• Gene: Acph-1 / 48445
• FlyBaseID: FBgn0000032
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_057445.4
• Gene: ACP6 / 51205
• HGNCID: 29609
• Length: 428
• Species: Homo sapiens
• Alignment Length: 469
• Identity: 107/469 - (22%)
• Similarity: 189/469 - (40%)
• Gaps: 118/469 - (25%)

  Fly    10 LVTSV-ARKMWNHPSQRWLILICVICLLSFALAN---SLHGYANAEGH-PVEISATLPGQLKFVH 69
            ::|.| :.::|..        :.|:..|::.|..   :|.....|:|. ||:.|..   :||.|.
Human     1 MITGVFSMRLWTP--------VGVLTSLAYCLHQRRVALAELQEADGQCPVDRSLL---KLKMVQ 54

  Fly    70 VIYRHGDRTPVDPYPTD---PW----------------------GDRKFWPTG------------ 97
            |::|||.|:|:.|.|.:   .|                      |.:.:.|..
Human    55 VVFRHGARSPLKPLPLEEQVEWNPQLLEVPPQTQFDYTVTNLAGGPKPYSPYDSQYHETTLKGGM 119

  Fly    98 -WGDLTNLGKQEHYDLGKWLRNRYSNLLP---PIYSNENIYVQSTDVDRTLMSAQSNLAGLYEPQ 158
             .|.||.:|.|:.:.||:.||..|...:|   |.::.:.::::||::.|.|.|.:..||||::.|
Human   120 FAGQLTKVGMQQMFALGERLRKNYVEDIPFLSPTFNPQEVFIRSTNIFRNLESTRCLLAGLFQCQ 184

  Fly   159 GEDIWNTDINWQPIPIHTSPEREDPILAAKAPCPAYD------------YELASLES--SPEFKA 209
            .|.         ||.|||. |.:..:|     .|.|.            .:.|||:.  |.:.|.
Human   185 KEG---------PIIIHTD-EADSEVL-----YPNYQSCWSLRQRTRGRRQTASLQPGISEDLKK 234

  Fly   210 LTEKHRNLFAYLSEKGGRPVKTFIDAQYLNNTLFIENLYNM----TLPKWTKMVYGREELTYVSN 270
            :.::   :....|:|        :|...|.:.:..|..:|:    .|.::.:|:    |...|..
Human   235 VKDR---MGIDSSDK--------VDFFILLDNVAAEQAHNLPSCPMLKRFARMI----EQRAVDT 284

  Fly   271 FAFAISSYTRKLARLKAGPLLKDIFQRFKEKSSGSLKPD--RSMWVYSAHDTTVASVLNALKLFE 333
            ..:.:....|:..::..||.|..:.....:....:..||  |.:::|:|||.|...:|..|.:|:
Human   285 SLYILPKEDRESLQMAVGPFLHILESNLLKAMDSATAPDKIRKLYLYAAHDVTFIPLLMTLGIFD 349

  Fly   334 LHSPPYTACIMMELRVD-ETNTPLVSIFYKNTTAEPLPLDIPGCGPS-CPLTKLMN---IYEDVL 393
            ...||:...:.|||... |:....|.::|......|     .||... |||...:|   :| .:.
Human   350 HKWPPFAVDLTMELYQHLESKEWFVQLYYHGKEQVP-----RGCPDGLCPLDMFLNAMSVY-TLS 408

  Fly   394 PVDWERECKLSTMM 407
            |..:...|..:.:|
Human   409 PEKYHALCSQTQVM 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acph-1	NP_733332.1	HP_HAP_like	64..361	CDD:132717	83/358 (23%)
ACP6	NP_057445.4	HP_HAP_like	49..379	CDD:132717	83/359 (23%)
		Substrate binding. /evidence=ECO:0000250	58..168		24/109 (22%)