DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Acph-1 and CG9449

DIOPT Version :9

Sequence 1:	NP_733332.1	Gene:	Acph-1 / 48445	FlyBaseID:	FBgn0000032	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	NP_001137976.1	Gene:	CG9449 / 40117	FlyBaseID:	FBgn0036875	Length:	404	Species:	Drosophila melanogaster

Alignment Length:	416	Identity:	147/416 - (35%)
Similarity:	229/416 - (55%)	Gaps:	46/416 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 FSRSRC----GSLVTSVARKMWNHPSQRWLILICVICLLSFALANSLHGYANAEGHPVEISATL- 61
            |:|..|    |.|:.|.            :|:.||        |:|          .||.:|.|
  Fly     6 FTRRHCLAMTGGLIASA------------VIIWCV--------AHS----------TVESTAKLY 40

  Fly    62 -PG----QLKFVHVIYRHGDRTPVDPYPTDPWGDRKFWPTGWGDLTNLGKQEHYDLGKWLRNRYS 121
             ||    .|:.:||::|||.|||.|.||.||:.:..::|.|||.:||.||:|.:::|.|||.||.
  Fly    41 DPGADKSTLELLHVVFRHGPRTPADTYPRDPYVNETYYPFGWGQITNNGKRELFNIGTWLRKRYG 105

  Fly   122 NLLPPIYSNENIYVQSTDVDRTLMSAQSNLAGLYEPQGEDI-WNTDINWQPIPIHTSPEREDPIL 185
            ..|.|.||.::::.|:|.|.||.|:.|:.||..:.|:|.|: ||:..||||||:.:....||.:|
  Fly   106 KFLAPNYSPDSVHAQATGVPRTHMTMQTVLAAFFPPKGTDMEWNSRFNWQPIPVFSQELNEDTLL 170

  Fly   186 AAKAPCPAYDYELASLESSPEFKALTEKHRNLFAYLSEKGGRPVKTFIDAQYLNNTLFIENLYNM 250
            ..:.|||.|...|..:...||.||..|.:..:|..|.|..|...|...|.|.|..||..|..:.:
  Fly   171 LVRKPCPRYFEALNEVYELPEVKAEIEPYLEMFKELEEHTGLSFKEPEDVQSLYLTLLAEQEWGL 235

  Fly   251 TLPKWTKMVYGREELTYVSNFAFAISSYTRKLARLKAGPLLKDIFQRFKEKSSGSLKPD-RSMWV 314
            .||:||. .|..|:|.:::..::..:.||.::.::|.||.||.:....::|.:|:|||. |.:::
  Fly   236 ELPEWTH-AYFPEKLQFLAEQSYIYNVYTPEMQKIKGGPFLKKMLDEMQQKKNGTLKPSGRKLFI 299

  Fly   315 YSAHDTTVASVLNALKLFELHSPPYTACIMMELRVD-ETNTPLVSIFYKN-TTAEPLPLDIPGCG 377
            |:.||:||.:||:|||::|...|.|::.|:.||..: ||....|.|:::| ...:...|.:|||.
  Fly   300 YAGHDSTVVNVLSALKIWERQMPRYSSMILFELHKNKETGDYWVEIYFRNDPKGQAQKLTLPGCE 364

  Fly   378 PSCPLTKLMNIYEDVLPVDW-ERECK 402
            ..|||.|::...:||:|.:. ::.|:
  Fly   365 FQCPLDKVLEFAKDVVPTEADDKRCE 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Acph-1	NP_733332.1	HP_HAP_like	64..361	CDD:132717	117/299 (39%)
CG9449	NP_001137976.1	HP_HAP_like	48..348	CDD:132717	117/300 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462390
Domainoid	1	1.000	170	1.000	Domainoid score	I3734
eggNOG	1	0.900	-	-		E1_KOG3720
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	219	1.000	Inparanoid score	I2297
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1221585at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm26563
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11567
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R958
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.930