DRSC/TRiP Functional Genomics Resources

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Protein Alignment Acph-1 and SPBC4.06

DIOPT Version :9

Sequence 1:NP_733332.1 Gene:Acph-1 / 48445 FlyBaseID:FBgn0000032 Length:455 Species:Drosophila melanogaster
Sequence 2:NP_595479.1 Gene:SPBC4.06 / 2540652 PomBaseID:SPBC4.06 Length:462 Species:Schizosaccharomyces pombe


Alignment Length:478 Identity:109/478 - (22%)
Similarity:178/478 - (37%) Gaps:158/478 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly    55 VEISATLPG-------QLKFVHVIYRHGDRTPVDP------YPTDPW----GDRKF--------- 93
            |:...::||       |||::.||:|||:|.||..      .|.| |    ..|:|         
pombe     9 VKFPDSVPGVDYPKQLQLKYLQVIFRHGERAPVKERLGSAGIPKD-WKLCNNARRFFAQIKGEKE 72

  Fly    94 W-------------------------PTG---WGDLTNLGKQEHYDLGKWLRNRY---SNLLPPI 127
            |                         |:|   .|:||:.|:.....||::||.||   ...||..
pombe    73 WSVLGFERKVESPVDTSLAAPTSDNSPSGVCIHGELTDFGRVTTRTLGEYLRERYVKQLKFLPDE 137

  Fly   128 YSN-ENIYVQSTDVDRTLMSAQSNLAGLYEPQGEDIWNTDI----NWQPIPIHTSPEREDPILAA 187
            .:| .::|:::|.:.|.|.|.:...:||| |:.:......:    ||.          ::.:|..
pombe   138 LNNYADVYMRATPMVRALESLEHVFSGLY-PESKRKMGLPVIFTRNWS----------DENLLPN 191

  Fly   188 KAPCPAYDYELASLESSPEFKALTEKHRNLFAYL-----SE-----KGGRPVKTFIDAQYLNNTL 242
            :..||    .|..|     ::...|:...|:..|     ||     ..|:||:.......|:..|
pombe   192 ENNCP----RLVQL-----YEEFAERAAKLYDPLLAGRASEMMSQFMNGQPVRVVSSHPRLSGLL 247

  Fly   243 FIENL-------YNMTL--PKWTKMVYGREELTYVSNFAFAISSYTRKLARLKAGPLLKDIFQRF 298
            ...|.       :|..|  .:|.     |:..|.|....|.....::.:.:|.||.||.|:..|.
pombe   248 DTINAAIGSHVDFNPNLRDEQWL-----RDAETAVVEEWFGGYKVSKLMRQLGAGSLLNDLSMRM 307

  Fly   299 KE----KSSGSLKPDRSMWVYSAHDTTVASVLNALKLFELHSPPYTACIMMEL------------ 347
            :.    :.:||  |...:.:|.|||.|:|::|.:|..|:...||:|:.:.|||            
pombe   308 ENFVVAEKNGS--PYHRLALYGAHDVTIAAILASLDAFDYRWPPFTSHLEMELFEDTSSKSDSQN 370

  Fly   348 ----------------RVDETNTPLV---------SIFYKNTTAEPLPLDIPGC--------GPS 379
                            ..|.:|:.:|         |.:|...|....|:.:..|        ...
pombe   371 QSGDNKTTDLKLFSDESTDASNSAIVAASNSARDMSDWYVRITYNSTPVVMGACRGQGYKGNDTI 435

  Fly   380 CPLTKLMNIYEDVLPVDWERECK 402
            |||:...:....:.||::...||
pombe   436 CPLSIFKDTVRALKPVEYHTMCK 458

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Acph-1NP_733332.1 HP_HAP_like 64..361 CDD:132717 95/411 (23%)
SPBC4.06NP_595479.1 His_Phos_2 25..366 CDD:278743 91/368 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 1 1.000 64 1.000 Domainoid score I2866
eggNOG 1 0.900 - - E1_KOG3720
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 64 1.000 Inparanoid score I1972
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - oto101133
orthoMCL 1 0.900 - - OOG6_100295
Panther 1 1.100 - - O PTHR11567
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R958
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
87.890

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