DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Acph-1 and Acp2

DIOPT Version :9

Sequence 1:	NP_733332.1	Gene:	Acph-1 / 48445	FlyBaseID:	FBgn0000032	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	NP_001343996.1	Gene:	Acp2 / 11432	MGIID:	87882	Length:	434	Species:	Mus musculus

Alignment Length:	379	Identity:	134/379 - (35%)
Similarity:	212/379 - (55%)	Gaps:	19/379 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 LKFVHVIYRHGDRTPVDPYPTDPWGDRKFWPTGWGDLTNLGKQEHYDLGKWLRNRYSNLLPPIYS 129
            |:||.::||||||:||..||.||:.:.| ||.|:|.||..|..:|::||:.||.||...|...|.
Mouse    33 LRFVTLLYRHGDRSPVKTYPKDPYQEEK-WPQGFGQLTKEGMLQHWELGQALRQRYHGFLNTSYH 96

  Fly   130 NENIYVQSTDVDRTLMSAQSNLAGLYEPQGEDIWNTDINWQPIPIHTSPEREDPILA-AKAPCPA 193
            .:.:||:|||.|||||||::|||||:.|.....:|.:|:|||||:||.|..||.:|. ...|||.
Mouse    97 RQEVYVRSTDFDRTLMSAEANLAGLFPPNEVQHFNPNISWQPIPVHTVPITEDRLLKFPLGPCPR 161

  Fly   194 YDYELASLESSPEFKALTEKHRNLFAYLSEKGGRPVKTFIDAQYLNNTLFIENLYNMTLPKWT-- 256
            |:........:||::..:.::......::.:.|....|......:.:|||.|..:.:.||.|.
Mouse   162 YEQLQNETRQTPEYQNRSIQNAQFLNMVANETGLTNVTLETIWNVYDTLFCEQTHGLLLPPWASP 226

  Fly   257 KMVYGREELTYVSNFA----FAISSYTRKLARLKAGPLLKDIFQRFKEKSSGSLKPDRSMWVYSA 317
            :.|   :.|:.:.:|:    |.|....:| |||:.|.||..|.:.....::.|..|  .:.||||
Mouse   227 QTV---QRLSQLKDFSFLFLFGIHEQVQK-ARLQGGVLLAQILKNLTLMATTSQFP--KLLVYSA 285

  Fly   318 HDTTVASVLNALKLFELHSPPYTACIMMELRVDETNTPLVSIFYKNTTAE-PLPLDIPGCGPSCP 381
            ||||:.::..||.::.....||.:|.:.||..::.....|.::::|.:.: |.||.:|||...||
Mouse   286 HDTTLVALQMALNVYNGKQAPYASCHIFELYQEDNGNFSVEMYFRNDSKKAPWPLILPGCPHRCP 350

  Fly   382 LTKLMNIYEDVLPVDWERECKLSTMMMTYEE----ANLGTATGILILIVIALLF 431
            |...:.:.|.|:|.||::||:|:......|.    |..|:...:||::::.:||
Mouse   351 LQDFLRLTEPVIPKDWQKECQLANDTADTEVIVALAVCGSILFLLIVLLLTILF 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Acph-1	NP_733332.1	HP_HAP_like	64..361	CDD:132717	109/302 (36%)
Acp2	NP_001343996.1	HP_HAP_like	33..330	CDD:132717	109/303 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846117
Domainoid	1	1.000	160	1.000	Domainoid score	I4032
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1217
Inparanoid	1	1.050	233	1.000	Inparanoid score	I3408
Isobase	1	0.950	-	0	Normalized mean entropy	S5170
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002540
OrthoInspector	1	1.000	-	-		mtm8763
orthoMCL	1	0.900	-	-		OOG6_100295
Panther	1	1.100	-	-	LDO	PTHR11567
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R958
SonicParanoid	1	1.000	-	-		X1300
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.870