DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5707 and Abhd8

DIOPT Version :9

Sequence 1:	NP_001246563.1	Gene:	CG5707 / 48422	FlyBaseID:	FBgn0026593	Length:	361	Species:	Drosophila melanogaster
Sequence 2:	NP_071864.2	Gene:	Abhd8 / 64296	MGIID:	1918946	Length:	439	Species:	Mus musculus

Alignment Length:	301	Identity:	64/301 - (21%)
Similarity:	107/301 - (35%)	Gaps:	83/301 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 LHGWLDNLGTWDKLLPLLPKHLG--VLCIDLPGHGYSSKLPEGIAYHFVDYLCVILRVMEEYRWQ 113
            :||...:|..|.:.|....: ||  |:..||.|||.||......||.|......:..:...|..:
Mouse   173 IHGVGGSLAIWKEQLDFFVR-LGYEVVAPDLAGHGASSAPQVAAAYTFYALAEDMRAIFTRYAKK 236

  Fly   114 KVSLMAHSMSAMLCFVFASLYP---HRTDM------------LVSIDIVKTRYRKPPSQIDYLRK 163
            :..|:.||.....|...|..||   |:..|            |.||      :..|...:..|..
Mouse   237 RNVLIGHSYGVSFCTFLAHEYPDLVHKVIMINGGGPTALEPSLCSI------FNMPTCVLHCLSP 295

  Fly   164 NIEGYIVEDERFANSKRQEPPAYTYTEMEQVLYKGTDYSVELENCRHILERNISRSTKFPAKFFF 228
            .:....:: ..||....:|         :|:|.:|..::|                :.|..:...
Mouse   296 CLAWSFLK-AGFARQGAKE---------KQLLKEGNAFNV----------------SSFVLRAMM 334

  Fly   229 SRDGRCKYYTE----FHTSPPFAAELARTIKNVPYCVIKGSESNYIDEQSDE------VIGILRE 283
            |.    :|:.|    :|      |||     .||..::.|....::..:.|:      ::..|:
Mouse   335 SG----QYWPEGDEVYH------AEL-----TVPVLLVHGMHDKFVPVEEDQRMAEILLLAFLK- 383

  Fly   284 NNPHFELHEVQGTHHVHLNNAQGVAAVINPFILHHRPPHLE 324
                  |.| :|:|.|.|...:.|..:::.|:|....|..|
Mouse   384 ------LIE-EGSHMVMLECPETVNTLLHEFLLWEPEPEAE 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5707	NP_001246563.1	MhpC	46..318	CDD:223669	62/293 (21%)
Abhd8	NP_071864.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	54..75
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	122..148
		MhpC	149..408	CDD:223669	60/290 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	415..439		1/3 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832175
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930