DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5707 and CG7632

DIOPT Version :9

Sequence 1:	NP_001246563.1	Gene:	CG5707 / 48422	FlyBaseID:	FBgn0026593	Length:	361	Species:	Drosophila melanogaster
Sequence 2:	NP_649302.1	Gene:	CG7632 / 40357	FlyBaseID:	FBgn0037071	Length:	330	Species:	Drosophila melanogaster

Alignment Length:	306	Identity:	137/306 - (44%)
Similarity:	196/306 - (64%)	Gaps:	12/306 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 NKEPMDVRIDMPWGYVVGKWYGNRQVRPILALHGWLDNLGTWDKLLPLLPKHLGVLCIDLPGHGY 84
            ||...::.|.:|||::.|||||.:.||||:.:|||.||.||:|.|.||||.||..|.||.||||.
  Fly    31 NKHFDEISIPVPWGHISGKWYGPKHVRPIVGMHGWQDNAGTFDTLAPLLPSHLSFLSIDAPGHGL 95

  Fly    85 SSKLPEGIAYHFVDYLCVILRVMEEYRWQKVSLMAHSMSAMLCFVFASLYPHRTDMLVSIDIVKT 149
            ||.||.|.:||.:|.:.:..|:||||.|.|:|::|||||::..|||::|:|.:.|:.|.:|::|.
  Fly    96 SSWLPPGTSYHSIDLVLITRRLMEEYNWDKISILAHSMSSINGFVFSALFPDKVDLFVGLDVLKP 160

  Fly   150 RYRKPPSQIDYLRKNIEGYIVEDERFANSKRQEPPAYTYTEMEQVLYKGTDYSVELENCRHILER 214
            ..|.....:|.|.:.||..:..:.|..:.  .|||||.:.::...|::|::.||.::.|:::|:|
  Fly   161 PVRSARGIVDSLTERIESALKLERRLKSG--SEPPAYDWDQLVTRLHEGSNKSVSIDACKYLLQR 223

  Fly   215 NISRSTKFPAKFFFSRDGRCK---YYTEFHTSPPFAAELARTIKNVPYCVIKGSESNYID--EQS 274
            |...||..|.|::||||.|.|   :|| .|...|.  |:||.|| .|:..||..::.|.:  |..
  Fly   224 NCKPSTHEPHKYYFSRDNRLKSSLFYT-LHQEVPM--EMARRIK-CPHLFIKALQAPYYERKEYF 284

  Fly   275 DEVIGILRENNPHFELHEVQGTHHVHLNNAQGVAAVINPFILHHRP 320
            |||:..| :.||.||.|||:||||||||..:.||.:||.||..:||
  Fly   285 DEVLAEL-QKNPLFEYHEVEGTHHVHLNEPEKVAPIINSFINRYRP 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5707	NP_001246563.1	MhpC	46..318	CDD:223669	123/276 (45%)
CG7632	NP_649302.1	MhpC	57..326	CDD:223669	123/275 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45448342
Domainoid	1	1.000	47	1.000	Domainoid score	I11659
eggNOG	1	0.900	-	-		E2759_KOG1454
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	52	1.000	Inparanoid score	I2617
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D109693at6656
OrthoFinder	1	1.000	-	-		FOG0001238
OrthoInspector	1	1.000	-	-		otm42436
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR43329
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X774
	10	9.900