Protein Alignment CG3558 and LOC1280932

DIOPT Version :10

• Sequence 1: NP_001137777.1
• Gene: CG3558 / 48421
• FlyBaseID: FBgn0025681
• Length: 1049
• Species: Drosophila melanogaster
• Sequence 2: XP_061516846.1
• Gene: LOC1280932 / 1280932
• VectorBaseID: AGAMI1_000354
• Length: 1130
• Species: Anopheles gambiae
• Alignment Length: 1148
• Identity: 628/1148 - (54%)
• Similarity: 760/1148 - (66%)
• Gaps: 176/1148 - (15%)

  Fly     6 SSGGGVASVGHVGPLRQRPIDAATDCDPRACYDSFCKHWQQAFEIIQHS---APPSHDDVLGVVS 67
            :.|||::||       .||.| ||:|||:|||||||.|||||:||||.|   ...|||||||||:
Mosquito    36 AGGGGLSSV-------IRPFD-ATECDPKACYDSFCIHWQQAYEIIQRSENYRSQSHDDVLGVVT 92

  Fly    68 HLDYMVTLLLVELHHCNKVSLPAAEASGPPAAPCLEFLLSENLLDKLYEWACTTGRYANAVRLEQ 132
            |||:||||||||||||||:|||....   |.|||||.|||||||||||||...||||||||||||
Mosquito    93 HLDHMVTLLLVELHHCNKLSLPGQPT---PPAPCLEHLLSENLLDKLYEWGIKTGRYANAVRLEQ 154

  Fly   133 LKLYELLVSHSRHQLLCHEPFLRPLLKILASSQGEIFPPDLEKRLVILLNQLCVVLMQNVHLLDL 197
            |||||.||||||||||.||||||||||:|||||.||:|||:||||||||||||||||||||||||
Mosquito   155 LKLYEQLVSHSRHQLLVHEPFLRPLLKLLASSQNEIYPPDVEKRLVILLNQLCVVLMQNVHLLDL 219

  Fly   198 FFFS-AQTQVQEQILNGNVAPPKSGTTTNFIIFSLLIPYVHREGSLGHQARDALLLCMALSQKNS 261
            |||| .|||......||.        .||||||||||||||||||||||||||||||||||||||
Mosquito   220 FFFSTTQTQQSHHASNGG--------HTNFIIFSLLIPYVHREGSLGHQARDALLLCMALSQKNS 276

  Fly   262 NIGTYIAQYSSICPLLVTGLGGLYSRLPNSIEISSIDWHRITPDDVTEIPELTLFMNALEFCNAV 326
            |:|||||.||||||:||||||||||||||.|||.::||:|||.|||||:||||||||:|||||||
Mosquito   277 NVGTYIATYSSICPVLVTGLGGLYSRLPNQIEIKTVDWYRITTDDVTEMPELTLFMNSLEFCNAV 341

  Fly   327 VQVAHEMIKQQLLDFMYQGFIVPVLGPAILQTLKGK-HFQTNIDSQISAMSYLDLILRSITEPGL 390
            |||||.||:||||||:||||:|||||||||||.||: .||||::||:|||:|.|||:||||||||
Mosquito   342 VQVAHTMIRQQLLDFLYQGFLVPVLGPAILQTFKGQGQFQTNVESQVSAMAYFDLIVRSITEPGL 406

  Fly   391 LRAFVRFLLDTEKFDGERILDALVERLNSPDANLCMVTMALFDTLLGLHCEDLMLELLLKFMLPG 455
            ::..:|||||.|||||:||||.|||||||.|:.|||||::|||:||.|:|||:||||:||::|..
Mosquito   407 IQIVIRFLLDEEKFDGQRILDVLVERLNSNDSRLCMVTLSLFDSLLSLNCEDIMLELMLKYLLHC 471

  Fly   456 KHVPISHRHKINKIDPYLNSSEFFLELSPDVMKRARDL------------ARPKSVHEPVV---- 504
            ||||||||:|||::|||..:.|:||.::||:||:...:            |...:..:|.|
Mosquito   472 KHVPISHRYKINRVDPYTQAVEYFLNITPDIMKKVNSVLSINNGGLASNGASSAAAGQPAVVATA 536

  Fly   505 ----SELTPLPSLPSPVM--SKTIGANWNYYGVH--TGDSLYANIQAYLFEAHWRIAQCQKDCLK 561
                ..||......|..:  |||||||||:||::  ||::|.||.||||.:|..||.||:..|.:
Mosquito   537 LGNHRTLTERGGSSSANLNVSKTIGANWNHYGLNTTTGETLLANYQAYLLDARNRIVQCKHACDQ 601

  Fly   562 WANSYRYQKWPR-----------HGQG--------------RVHAHALELARQFFSE-------- 593
            |.|.|||||..:           :|.|              .|.|..:::.:.|..|
Mosquito   602 WNNVYRYQKLSKANFTGAPNVAANGGGGVGSSGQNSLVNPEDVRALKVQMIKDFLREFSIDSGIG 666

  Fly   594 ---------------------------------FGGGPIAANETGEKQLDSLQSIGESSGYESFK 625
                                             ||||.|..  :..||||||||||:||||||.
Mosquito   667 DCGDSLQQQQQQQQNHHHTSVTGTSSSASSAIMFGGGSIGT--SSGKQLDSLQSIGDSSGYESL- 728

  Fly   626 WRPADEESEATDTTVA--TTASEADMDHNSSSLSSVLGASGKRESWRTSNSNRNELILTDLDFSE 688
                :..|:.::..||  |...|..:......:          ::|:.| |.|.|.| .|||.||
Mosquito   729 ----NVFSQTSNDLVAPGTMPQEPQLKQQQQRI----------DAWKVS-SVREEPI-GDLDLSE 777

  Fly   689 DLFAQGTVSLGPFLNAIWGKLQTFTSNSLYVNLHLTGLITRLAWYPLPLIHSLLLRSDIAITSDT 753
            ||||||||||||||.||||||||||||.||||||||||||.|..:||||:||:|||.||..||||
Mosquito   778 DLFAQGTVSLGPFLTAIWGKLQTFTSNCLYVNLHLTGLITHLTLFPLPLLHSILLRPDIPTTSDT 842

  Fly   754 PSFHQVLRILKQQIDAELPVTEDSLEIIDVARSSLIDREFRLANARKGNEGSPMHHSQQQQMVTN 818
            |||||||:|||||||||||.|::||||:|:|||.|:||||||.|.||    :.:..:...:::..
Mosquito   843 PSFHQVLKILKQQIDAELPDTDESLEIVDMARSFLVDREFRLVNMRK----NAIESAASGKLLNG 903

  Fly   819 SGQQQGQLRSAYATLSAATPVQATPTSAYDPFKRSDNKRRSISKSITSMFSRKSASTSTAPPNGS 883
            .|.      |..::||..||:|.||:|:||||||.|.||:|||.|.:::|.|.          ||
Mosquito   904 GGS------SMTSSLSQTTPMQLTPSSSYDPFKRQDGKRKSISNSFSNIFRRP----------GS 952

  Fly   884 SASSGLSQIYAFFTGAASNLVGNNASNDGRGISQAQTSAGTCETSLSTQPPAGASRTGANATSTA 948
            .|||||:||..|||| :||..|.|.|.:||...|:.|.|     |::...|.|..:....:.|:.
Mosquito   953 VASSGLAQIVEFFTG-SSNSNGLNHSPNGRQQPQSYTPA-----SMNVPSPVGQQQHQHQSVSSV 1011

  Fly   949 ASGSNSSIAGSTLTLSAQSNTTTHSASTLHGLDGG---PS---TGGFNS----EPASLDSVASMG 1003
            ...|...| ||:...|.::.|...|..|.....||   ||   :.|.|.    .|.||:.    |
Mosquito  1012 MPPSGLLI-GSSRRESREAETQFMSIDTSSLQAGGINAPSGHVSNGSNGNDLLHPHSLEH----G 1071

  Fly  1004 IIASTSGTERSRDLALCAVLMDEWLKELAAIAQEQSVVLVTEQ 1046
            :.:.:.|:||..:||:.|||:||||:||:|:.|||.:::::||
Mosquito  1072 LTSYSVGSERQLNLAIGAVLLDEWLRELSAVTQEQCIMMLSEQ 1114

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3558	NP_001137777.1	RAI16-like	101..452	CDD:370927	281/352 (80%)
		DUF5917	698..791	CDD:466037	73/92 (79%)
		DUF5585	795..>1011	CDD:465521	74/225 (33%)
		KELAA	1012..1043	CDD:466035	17/30 (57%)
LOC1280932	XP_061516846.1	None