Protein Alignment CG3558 and fhip1b

DIOPT Version :9

• Sequence 1: NP_001137777.1
• Gene: CG3558 / 48421
• FlyBaseID: FBgn0025681
• Length: 1049
• Species: Drosophila melanogaster
• Sequence 2: XP_031753295.1
• Gene: fhip1b / 100490226
• XenbaseID: XB-GENE-6040539
• Length: 1045
• Species: Xenopus tropicalis
• Alignment Length: 1232
• Identity: 328/1232 - (26%)
• Similarity: 479/1232 - (38%)
• Gaps: 393/1232 - (31%)

  Fly     2 WLRQSSGGGVASVGHVGPLRQRPIDAATDCDPRACYDSFCKHWQQAFEIIQHSAPP----SHDDV 62
            ||.:.:..|..|....|...|..:.|    ||..|...|..||.|...|::...|.    |.||:
 Frog     3 WLSKLNPRGAGSKAGRGATLQPLVTA----DPETCLMVFKNHWSQVLRILERHGPSAETVSADDL 63

  Fly    63 LGVVSHLDYMVTLLLVELHHCNKVSLPAAEASGPPAAPCLEFLLSENLLDKLYEWACTTGRYANA 127
            ..|.::...||:||..||         ..:..||  .|.|.::.||.:::::.:|. ....:...
 Frog    64 SSVRNNTYQMVSLLAEEL---------PQDGDGP--GPILAYMASEGIMERILQWH-RRREFTED 116

  Fly   128 VRLEQLKLYELLVSHSRHQLLCHEPFLRPLLKILASSQGEIFPPDLEKRLVILLNQLCVVLMQNV 192
            .::|||||||:|:|.||..||.::|.||||:.:|::.......|.||..||:|||||||.|.:..
 Frog   117 KKVEQLKLYEMLISQSRQPLLRYQPILRPLVTLLSTFSPGPAAPVLENNLVLLLNQLCVSLAREP 181

  Fly   193 HLLDLFFFSAQTQVQEQILNGNVAPPKSGTTTNFIIFSLLIPYVHREGSLGHQARDALLLCMALS 257
            ..|:|||               ..|..|....|.:|||||:|::|.||.:|.||||||||.||:|
 Frog   182 STLELFF---------------QGPSGSDGPANLLIFSLLVPFIHHEGVIGQQARDALLLIMAMS 231

  Fly   258 QKNSNIGTYIAQYSSICPLLVTGLGGLYSRLPNSIEISSIDWHRITPDDVTEIPELTLFMNALEF 322
            .:|..:..||.:.|..||:|.|||..|||.||..||:...|||.:..:|...:..|.||||:|||
 Frog   232 SENPTMAKYITENSFFCPILATGLSALYSSLPRKIEVRGDDWHFLRREDWIGVSSLVLFMNSLEF 296

  Fly   323 CNAVVQVAHEMIKQQLLDFMYQGFIVPVLGPAILQTLKGKHFQTNIDSQISAMSYLDLILRSITE 387
            ||||.||||.:::.||:::::.||:|||:|||:        .:|:|:..|::.:||:|.||||:|
 Frog   297 CNAVTQVAHPLVQNQLVEYIHNGFLVPVMGPAL--------HKTSIEEMIASTAYLELFLRSISE 353

  Fly   388 PGLLRAFVRFLLDTEKFDGERILDALVERLNSPDANLCMVTMALFDTLLGLHCEDLMLELLLKFM 452
            ..||:.|:||:| ..:.|...||..|:.|:.| ::.||||::.||.|||.:.|||.:|:|:|:::
 Frog   354 TPLLKTFLRFIL-LHRHDSSTILQTLISRIAS-NSRLCMVSLTLFRTLLNITCEDFLLQLVLRYL 416

  Fly   453 LPGKHVPISHRHKINKIDPYLNSSEFFLELSPDVMK--------RARDLARPKSVH-EPVV--SE 506
            :|..||.:|.|..|..:|.|..:::.||.|.|...:        |..:.|.....| .|.:  |.
 Frog   417 IPCNHVMLSQRRAIKDLDLYSKTADKFLSLIPRCCRKENLCPQDREEEHATWSKAHGSPSIDTSS 481

  Fly   507 LT--PLPSLP--------------------SPVMS---KTIGAN------WNYYGVHTGDSLYAN 540
            :|  |.||.|                    ||..|   ..||:.      |:...     .|..|
 Frog   482 VTTVPRPSTPSRMGFFMRQSNAAPESPSSRSPSFSLPDAVIGSPRHSSLCWDEVA-----ELDGN 541

  Fly   541 IQAYLFEAHWRIAQCQKDCLKWANSY--------------------------------------- 566
            ...||.||...|.:|...|..|:..|
 Frog   542 YLEYLQEARAAIDRCVHACRAWSAPYDGEEPSPRSLSPSTPDEVTVSPDYFSPPPFIKAHDGKER 606

  Fly   567 ---RYQKWP--------------------------RHGQGRVHAHALELARQFFSE---FGGG-- 597
               |:...|                          ||.:|.|...::.:.....:|   :.||
 Frog   607 EARRHSATPRTKKRSLQEEGDGERLSTLNGGGAEERHTEGSVDGASVPVLNGALTEEQGYLGGTP 671

  Fly   598 -----------------------------------PIAANETGEKQLDSLQSIGESSGYESFKWR 627
                                               |:..:|.|.:|    :|.|:...:.|.||.
 Frog   672 RGPAMGGHCAEDVEVKKVKREPAEERENSHSEERKPLLVSENGSQQ----KSYGKQQPWGSIKWE 732

  Fly   628 PADEESEATDTTVATTASEADMDH-NSSSLSSVLG--ASGKRESWR------------------- 670
            ..:......:..:|...:|.:..| |...|...||  .:..||:.|
 Frog   733 TPESVDNLIEELLARAPAETNGAHINIEKLGEELGEMENNMREAARQEELTAEQHQGPTKEEQEE 797

  Fly   671 -----------TSNSNRNELILTDLDFSEDLFAQ--GTVSLGPFLNAIWGKLQTFTSNSLYVNLH 722
                       .|.::...|||     |..|.||  |....|||:..::.||:|...||||||..
 Frog   798 VEYQNCEAEITKSRADSMSLIL-----SSPLRAQNGGQPFTGPFIGVLFAKLETMLQNSLYVNFL 857

  Fly   723 LTGLITRLAWYPLPLIHSLLLRSDIAITSDTPSFHQVLRILKQQIDAELPVTEDSLEIIDVARSS 787
            |||:||:||.:|.||:.|.||.:::.......|..|||..:|.:|:|.....||...::..|:..
 Frog   858 LTGIITQLACHPQPLLRSFLLNTNMVFQPSVKSLVQVLGSVKNKIEAFAASQEDFPTLLFKAKKF 922

  Fly   788 LIDREFRLANARKGNEGSPMHHSQQQQMVTNSGQQQGQLRSAYATLSAATPVQATPTSAYDPFKR 852
            ||.|             ..:..|:.|..|                               ...:|
 Frog   923 LIAR-------------GKLDWSENQMSV-------------------------------PALRR 943

  Fly   853 SDNKRRSISKSITSMFSRKSASTSTAPPNGSSASSGLSQIYAFFTGAASNLVGNNASNDGRGISQ 917
            ||...:|...||..:..|
 Frog   944 SDTLVKSRKPSIGELILR----------------------------------------------- 961

  Fly   918 AQTSAGTCETSLSTQPPAGASRTGANATSTAASGSNSSIAGSTLTLSAQSNTTTHSASTLHGLDG 982
                        .|..|..|.:....|......|                       ..||.|.|
 Frog   962 ------------HTNSPTRARQAAQMAFQHVRDG-----------------------QVLHALSG 991

  Fly   983 GPSTGGFNSEPASLDSVASMGIIASTSGTE----RSRDLALCAVLMDEWLKELAAIAQEQSV 1040
            .                   .|..|::..:    |.::...|||:..|::|||||||||.:|
 Frog   992 S-------------------SIFKSSAEKQNEALRVKNAVYCAVIFTEFMKELAAIAQEHAV 1034

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3558	NP_001137777.1	RAI16-like	101..452	CDD:287259	149/350 (43%)
		LbR-like	898..979	CDD:248061	6/80 (8%)
fhip1b	XP_031753295.1	RAI16-like	91..416	CDD:370927	149/350 (43%)
		PHA03169	560..>806	CDD:223003	31/249 (12%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	134	1.000	Domainoid score	I4966
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	451	1.000	Inparanoid score	I1573
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D141539at2759
OrthoFinder	1	1.000	-	-		FOG0003063
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR21705
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2039
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.160