DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(2)k10201 and ZNF511

DIOPT Version :9

Sequence 1:	NP_788296.1	Gene:	l(2)k10201 / 48373	FlyBaseID:	FBgn0016970	Length:	221	Species:	Drosophila melanogaster
Sequence 2:	NP_665805.2	Gene:	ZNF511 / 118472	HGNCID:	28445	Length:	252	Species:	Homo sapiens

Alignment Length:	224	Identity:	60/224 - (26%)
Similarity:	89/224 - (39%)	Gaps:	63/224 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 PAPSLAPFKKLG-------------------------VLVDIDDI--------LGEQDAAAARIR 65
            ||...|||:.:.                         |::.:.|:        ...|.|...::.
Human    27 PAAGAAPFRFVARPVRFPREHQFFEDGDVQRHLYLQDVIMQVADVPEKPRVPAFACQVAGCCQVF 91

  Fly    66 DNIDK-EQSYS------CVECRKMLPTAHLLDLHITEQHDCYFAASVERGDKPMFSCFLEECTIK 123
            |.:|. |..|.      |..|::..|:.||||.||.|.||..|....||.|  |:.|.:|.||.|
Human    92 DALDDYEHHYHTLHGNVCSFCKRAFPSGHLLDAHILEWHDSLFQILSERQD--MYQCLVEGCTEK 154

  Fly   124 FHTARQRKDHCIITHKLPANYRFDH-SKNRGKQKHQG------KSKPNSMEV-DEVIEETKS--- 177
            |.|:|.||||.:..|..||::|||. .|:|.....:.      :|:..:||: .|.:..:.:
Human   155 FKTSRDRKDHMVRMHLYPADFRFDKPKKSRSPASAEAPGDSGERSEGEAMEICSEPVAASPAPAG 219

  Fly   178 --------LPYVKAFSFGHQTQRSFYTGK 198
                    :|  ....||....|.|.:.|
Human   220 ERRIYRHRIP--STICFGQGAARGFKSNK 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)k10201	NP_788296.1	None
ZNF511	NP_665805.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	177..221		8/43 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165140574
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4173
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S8333
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1360267at2759
OrthoFinder	1	1.000	-	-		FOG0007118
OrthoInspector	1	1.000	-	-		oto89819
orthoMCL	1	0.900	-	-		OOG6_105605
Panther	1	1.100	-	-	LDO	PTHR21354
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4629
SonicParanoid	1	1.000	-	-		X5205
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	12	11.690