Protein Alignment deltaTry and TMPRSS5

DIOPT Version :10

• Sequence 1: NP_523694.2
• Gene: deltaTry / 48343
• FlyBaseID: FBgn0010358
• Length: 253
• Species: Drosophila melanogaster
• Sequence 2: NP_110397.2
• Gene: TMPRSS5 / 80975
• HGNCID: 14908
• Length: 457
• Species: Homo sapiens
• Alignment Length: 278
• Identity: 97/278 - (34%)
• Similarity: 128/278 - (46%)
• Gaps: 46/278 - (16%)

  Fly    15 LGGTVPEGLLPQ--------------------LDGRIVGGSATTISSFPWQISLQRSGSHSCGGS 59
            |||.:.|...|:                    |..|||||.:.....:|||.|:.....|:||||
Human   182 LGGFLEEAWQPRNNCTSGQVVSLRCSECGARPLASRIVGGQSVAPGRWPWQASVALGFRHTCGGS 246

  Fly    60 IYSSNVIVTAAHCLQSVSASVLQIRAGSSYWSSGGVTFSVSSFKNHEG-----------YNANTM 113
            :.:...:||||||:.|...:.|      |.|.......|.|:.:.|:|           |:|...
Human   247 VLAPRWVVTAAHCMHSFRLARL------SSWRVHAGLVSHSAVRPHQGALVERIIPHPLYSAQNH 305

  Fly   114 VNDIAIIKINGALTFSSTIKAIGLASSNP--ANGAAASVSGWGTLSYGSSSIPSQLQYVNVNIVS 176
            ..|:|::::..||.||.|:.|:.|.:...  ..|:...|||||......:.....||...|.:.|
Human   306 DYDVALLRLQTALNFSDTVGAVCLPAKEQHFPKGSRCWVSGWGHTHPSHTYSSDMLQDTVVPLFS 370

  Fly   177 QSQCASSTYGYGSQIRSTMICAA-ASGK-DACQGDSGGPLV--SGGV--LVGVVSWGYGCAYSNY 235
            ...|.||.. |...:...|:||. ..|: ||||||||||||  .|..  ||||||||.|||..|:
Human   371 TQLCNSSCV-YSGALTPRMLCAGYLDGRADACQGDSGGPLVCPDGDTWRLVGVVSWGRGCAEPNH 434

  Fly   236 PGVYADVAALRSWVISNA 253
            |||||.||....|:...|
Human   435 PGVYAKVAEFLDWIHDTA 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
deltaTry	NP_523694.2	Tryp_SPc	30..249	CDD:214473	89/237 (38%)
TMPRSS5	NP_110397.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		SRCR_2	116..213	CDD:464747	5/30 (17%)
		Tryp_SPc	217..448	CDD:214473	89/237 (38%)