Protein Alignment GstD8 and CLIC3

DIOPT Version :10

• Sequence 1: NP_524916.1
• Gene: GstD8 / 48341
• FlyBaseID: FBgn0010044
• Length: 212
• Species: Drosophila melanogaster
• Sequence 2: NP_004660.2
• Gene: CLIC3 / 9022
• HGNCID: 2064
• Length: 236
• Species: Homo sapiens
• Alignment Length: 202
• Identity: 48/202 - (23%)
• Similarity: 79/202 - (39%)
• Gaps: 40/202 - (19%)

  Fly    12 CRSVIMTAKALGVDLNMKLLKVMDGEQLKPEFVKLNPQHCIPTLVDDGFSIWESRAILIYLVEKY 76
            |:.:.|.....||...:..:.......:..:|.   |...:|.|:.|..:..::..|..:|.|..
Human    25 CQRLFMVLLLKGVPFTLTTVDTRRSPDVLKDFA---PGSQLPILLYDSDAKTDTLQIEDFLEETL 86

  Fly    77 GADD--SLYPSDPQKKAVVNQRLYFDMGTLFQSFVEAIYPQIRNNHPADPEAM-QKVDSAFGHLD 138
            |..|  ||.|...:.....|     |:...|.:|       |:|..||..||: |::..|...||
Human    87 GPPDFPSLAPRYRESNTAGN-----DVFHKFSAF-------IKNPVPAQDEALYQQLLRALARLD 139

  Fly   139 TFL----------EDQ------EYVAGDCLTIADIALLASVSTFEVVDFDIAQYP------NVAR 181
            ::|          |.|      .::.||.||:||.:||..:...:.|.....|.|      .|.|
Human   140 SYLRAPLEHELAGEPQLRESRRRFLDGDRLTLADCSLLPKLHIVDTVCAHFRQAPIPAELRGVRR 204

  Fly   182 WYENAKE 188
            :.::|.:
Human   205 YLDSAMQ 211

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstD8	NP_524916.1	GST_N_Delta_Epsilon	1..74	CDD:239343	11/61 (18%)
		GST_C_Delta_Epsilon	88..204	CDD:198287	31/124 (25%)
CLIC3	NP_004660.2	Required for insertion into the membrane. /evidence=ECO:0000250	1..88		12/65 (18%)
		O-ClC	5..229	CDD:129941	48/202 (24%)
		G-site. /evidence=ECO:0000305|PubMed:28198360, ECO:0000305|PubMed:37759794	22..25		48/202 (24%)