DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstD8 and CAM1

DIOPT Version :9

Sequence 1:	NP_524916.1	Gene:	GstD8 / 48341	FlyBaseID:	FBgn0010044	Length:	212	Species:	Drosophila melanogaster
Sequence 2:	NP_015277.1	Gene:	CAM1 / 856059	SGDID:	S000005969	Length:	415	Species:	Saccharomyces cerevisiae

Alignment Length:	214	Identity:	52/214 - (24%)
Similarity:	90/214 - (42%)	Gaps:	50/214 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 KALGVDLNMKLLKVMDGEQLKPEFVKLNPQHCIPTLV-DDGFSIWESRAILIYLV---------- 73
            |||.:|     :||:..:....:|.:..|...:|..| ..|:.:.|:.||..|||
Yeast    22 KALKLD-----VKVVTPDAAAEQFARDFPLKKVPAFVGPKGYKLTEAMAINYYLVKLSQDDKMKT 81

  Fly    74 EKYGADDSLYPSDPQKKAVVNQRLYFDMGTLFQSFVEA-IYPQIRN-----------NHPADPEA 126
            :..||||.|   :.|.:.:           .:||...: :..||.|           |..:...|
Yeast    82 QLLGADDDL---NAQAQII-----------RWQSLANSDLCIQIANTIVPLKGGAPYNKKSVDSA 132

  Fly   127 MQKVDSAFGHLDTFLEDQEYVAGDCLTIADIALLASVST--FEVVDFDI---AQYPNVARWYENA 186
            |..||......:..|::..|:|.:.:::||: :.||:.|  ||.: |..   ||:|.:.||: |.
Yeast   133 MDAVDKIVDIFENRLKNYTYLATENISLADL-VAASIFTRYFESL-FGTEWRAQHPAIVRWF-NT 194

  Fly   187 KEVTPGWEENWDGVQLIKK 205
            ...:|..::.:...:...|
Yeast   195 VRASPFLKDEYKDFKFADK 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstD8	NP_524916.1	GstA	1..188	CDD:223698	50/195 (26%)
		GST_N_Delta_Epsilon	1..74	CDD:239343	17/64 (27%)
		GST_C_Delta_Epsilon	88..204	CDD:198287	29/132 (22%)
CAM1	NP_015277.1	GST_N_EF1Bgamma	4..73	CDD:239342	17/55 (31%)
		GST_C_EF1Bgamma_like	92..214	CDD:198290	30/136 (22%)
		EF1G	255..359	CDD:395522
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345059
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740