DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstD8 and URE2

DIOPT Version :9

Sequence 1:	NP_524916.1	Gene:	GstD8 / 48341	FlyBaseID:	FBgn0010044	Length:	212	Species:	Drosophila melanogaster
Sequence 2:	NP_014170.1	Gene:	URE2 / 855492	SGDID:	S000005173	Length:	354	Species:	Saccharomyces cerevisiae

Alignment Length:	210	Identity:	56/210 - (26%)
Similarity:	89/210 - (42%)	Gaps:	42/210 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 VIMTAKALGVDLNMKLLKVMDGEQLKPEFVKLNPQHCIPTLVD---DGFSIWESRAILIYLVEKY 76
            |.:....||...|...|....||...||||.:||...:|.|:|   |..|||||.|||::||.||
Yeast   128 VAIVLSELGFHYNTIFLDFNLGEHRAPEFVSVNPNARVPALIDHGMDNLSIWESGAILLHLVNKY 192

  Fly    77 GADDS---LYPSDPQKKAVVNQRLYFD-------MGTLFQ----------SFVEAIYPQIRNNHP 121
            ..:..   |:..|...::.:|..|:|.       :|....          |.||....::|..:.
Yeast   193 YKETGNPLLWSDDLADQSQINAWLFFQTSGHAPMIGQALHFRYFHSQKIASAVERYTDEVRRVYG 257

  Fly   122 ADPEAM-QKVDSAFGHLDT-----------------FLEDQEYVAGDCLTIADIALLASVSTFEV 168
            ....|: ::.::....|||                 |.:...::.||.|||||:|.:...:..:.
Yeast   258 VVEMALAERREALVMELDTENAAAYSAGTTPMSQSRFFDYPVWLVGDKLTIADLAFVPWNNVVDR 322

  Fly   169 VDFDI-AQYPNVARW 182
            :..:| .::|.|.:|
Yeast   323 IGINIKIEFPEVYKW 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstD8	NP_524916.1	GstA	1..188	CDD:223698	56/210 (27%)
		GST_N_Delta_Epsilon	1..74	CDD:239343	26/61 (43%)
		GST_C_Delta_Epsilon	88..204	CDD:198287	25/131 (19%)
URE2	NP_014170.1	GST_N_Ure2p_like	114..194	CDD:239346	29/65 (45%)
URE2	NP_014170.1	GST_C_Ure2p	208..350	CDD:198326	25/130 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	52	1.000	Domainoid score	I2827
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	68	1.000	Inparanoid score	I1709
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
TreeFam	1	0.960	-	-
	9	8.720