DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstD8 and TEF4

DIOPT Version :9

Sequence 1:	NP_524916.1	Gene:	GstD8 / 48341	FlyBaseID:	FBgn0010044	Length:	212	Species:	Drosophila melanogaster
Sequence 2:	NP_012842.1	Gene:	TEF4 / 853781	SGDID:	S000001564	Length:	412	Species:	Saccharomyces cerevisiae

Alignment Length:	196	Identity:	47/196 - (23%)
Similarity:	84/196 - (42%)	Gaps:	34/196 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 LKVMDGEQLKPEFVKLNPQHCIPT-LVDDGFSIWESRAILIYLVEKYGADDS----LYPSDPQKK 90
            :|::|.|| ..||..|.|....|. |...|..:.|:.||..||..:. ||:.    |..||..:|
Yeast    28 VKIVDLEQ-SSEFASLFPLKQAPAFLGPKGLKLTEALAIQFYLANQV-ADEKERARLLGSDVIEK 90

  Fly    91 -------AVVNQRLYFDMGTLFQSFVEAIYPQIRNNHPADPEAMQKVDSAFGHLDTFLEDQEYVA 148
                   ::.|..:..::...|.|| :.:.|..:.:..|   ...|:|:.....|..|.|..:||
Yeast    91 SQILRWASLANSDVMSNIARPFLSF-KGLIPYNKKDVDA---CFVKIDNLAAVFDARLRDYTFVA 151

  Fly   149 GDCLTIADIALLASVSTFEVVDFDI---------AQYPNVARWYENAKEVTPGWEENWDGVQLIK 204
            .:.:::.|:....|.:      |.:         |::|::.||: |....:|..:..:..|:|.:
Yeast   152 TENISLGDLHAAGSWA------FGLATILGPEWRAKHPHLMRWF-NTVAASPIVKTPFAEVKLAE 209

  Fly   205 K 205
            |
Yeast   210 K 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstD8	NP_524916.1	GstA	1..188	CDD:223698	43/177 (24%)
		GST_N_Delta_Epsilon	1..74	CDD:239343	16/43 (37%)
		GST_C_Delta_Epsilon	88..204	CDD:198287	25/131 (19%)
TEF4	NP_012842.1	GST_N_EF1Bgamma	4..72	CDD:239342	16/44 (36%)
		GST_C_EF1Bgamma_like	89..211	CDD:198290	26/133 (20%)
		EF1G	253..356	CDD:395522
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345069
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740