DRSC/TRiP Functional Genomics Resources

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Protein Alignment GstD8 and GDAP1

DIOPT Version :10

Sequence 1:NP_524916.1 Gene:GstD8 / 48341 FlyBaseID:FBgn0010044 Length:212 Species:Drosophila melanogaster
Sequence 2:NP_061845.2 Gene:GDAP1 / 54332 HGNCID:15968 Length:358 Species:Homo sapiens


Alignment Length:255 Identity:45/255 - (17%)
Similarity:93/255 - (36%) Gaps:82/255 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 HPCSAPCRSVIMTAKALGV---DLNMKLLKVMDGEQLKPEFVKLNPQHCIPTLVDDGFSIWESRA 67
            |..|:....:::..|||..   |:::.|     .|..:|.|::||....:|.|:.....|.|:..
Human    33 HSFSSQKVRLVIAEKALKCEEHDVSLPL-----SEHNEPWFMRLNSTGEVPVLIHGENIICEATQ 92

  Fly    68 ILIYLVEKYGADDSLYPSDPQKKAVVNQRLY-------------FDMGTLF--QSFVEAIYP--- 114
            |:.||.:.: .|:......|.|:::...|:.             :..|.:.  :..|:::.|   
Human    93 IIDYLEQTF-LDERTPRLMPDKESMYYPRVQHYRELLDSLPMDAYTHGCILHPELTVDSMIPAYA 156

  Fly   115 ------QIRN----------NHPADPEA------------------------MQKVDSAFGHLDT 139
                  ||.|          .:|...||                        :.:::.....::|
Human   157 TTRIRSQIGNTESELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVKYLKKILDELEKVLDQVET 221

  Fly   140 FLE----------DQEYVAGDCLTIADIALLASVSTFEVVDFDIAQY-----PNVARWYE 184
            .|:          .|.::.|:..|:||::|..::...:.:.|....:     ||:..:||
Human   222 ELQRRNEETPEEGQQPWLCGESFTLADVSLAVTLHRLKFLGFARRNWGNGKRPNLETYYE 281

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GstD8NP_524916.1 GST_N_Delta_Epsilon 1..74 CDD:239343 19/70 (27%)
GST_C_Delta_Epsilon 88..204 CDD:198287 24/170 (14%)
GDAP1NP_061845.2 GST_N_GDAP1 26..98 CDD:239350 18/69 (26%)
GST_C_GDAP1 179..289 CDD:198336 16/103 (16%)
Required for mitochondrial localization 320..358
Blue background indicates that the domain is not in the aligned region.

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