DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstD8 and GstE12

DIOPT Version :9

Sequence 1:	NP_524916.1	Gene:	GstD8 / 48341	FlyBaseID:	FBgn0010044	Length:	212	Species:	Drosophila melanogaster
Sequence 2:	NP_001246500.1	Gene:	GstE12 / 37960	FlyBaseID:	FBgn0027590	Length:	223	Species:	Drosophila melanogaster

Alignment Length:	218	Identity:	82/218 - (37%)
Similarity:	123/218 - (56%)	Gaps:	10/218 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 YYHPCSAPCRSVIMTAKALGVDLNMKLLKVMDGEQLKPEFVKLNPQHCIPTLVDDGFSIWESRAI 68
            ||...|.|.|:|::||||:|:||.::.:.::.||.|.|||:||||||.||||:|...:|.:|.||
  Fly     7 YYATLSPPSRAVLLTAKAIGLDLELRPINLLKGEHLTPEFLKLNPQHTIPTLIDGEATIIDSHAI 71

  Fly    69 LIYLVEKYG-ADDSLYPSDPQKKAVVNQRLYFDMGTLFQSFVEAIYPQIRNNHPAD--PEAMQKV 130
            ..||||||| .:..|||.:..::|.|:.||:.|.|.|| :.:..:|..|......|  .:.:..:
  Fly    72 CAYLVEKYGQKEQQLYPKELVQRANVDARLHLDSGHLF-ARLRFLYEPILYYGSTDCSIDKIAYI 135

  Fly   131 DSAFGHLDTFLEDQEYVAGDCLTIADIALLASV-STFEVVDFDIAQYPNVARWYENAKEVTPGWE 194
            ...:..|:.||:||.|:.|..|||||...:|:| |..:....|..::|.:..|.:...|:....|
  Fly   136 QKCWEILEGFLKDQPYLCGSDLTIADFCAVATVTSVNDTAPIDEFKFPKMHAWLKRLAELPYYQE 200

  Fly   195 ENWDGVQLIK-----KLVQERNE 212
            .|.||...:|     ||.:.|.:
  Fly   201 VNGDGADELKSIFKAKLAENRGK 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstD8	NP_524916.1	GstA	1..188	CDD:223698	73/187 (39%)
		GST_N_Delta_Epsilon	1..74	CDD:239343	36/69 (52%)
		GST_C_Delta_Epsilon	88..204	CDD:198287	34/118 (29%)
GstE12	NP_001246500.1	GST_N_Delta_Epsilon	4..77	CDD:239343	36/69 (52%)
		GstA	6..201	CDD:223698	74/194 (38%)
		GST_C_Delta_Epsilon	92..210	CDD:198287	34/118 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460273
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D118089at33392
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	11	10.800