DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstD8 and GstE11

DIOPT Version :9

Sequence 1:	NP_524916.1	Gene:	GstD8 / 48341	FlyBaseID:	FBgn0010044	Length:	212	Species:	Drosophila melanogaster
Sequence 2:	NP_001286575.1	Gene:	GstE11 / 37128	FlyBaseID:	FBgn0034354	Length:	225	Species:	Drosophila melanogaster

Alignment Length:	220	Identity:	88/220 - (40%)
Similarity:	130/220 - (59%)	Gaps:	14/220 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 YYHPCSAPCRSVIMTAKALGVDLNMKLLKVMDGEQLKPEFVKLNPQHCIPTLVDDGFSIWESRAI 68
            ||.|.|.|||:|::||.|||::|:::|:.|..||....||:|||.||.||.|.|:|..:.:|..|
  Fly     8 YYAPRSPPCRAVLLTAAALGLELDLRLVNVKAGEHKSAEFLKLNAQHTIPVLDDNGTIVSDSHII 72

  Fly    69 LIYLVEKYG--ADDSLYPSDPQKKAVVNQRLYFDMGTLFQSFVEAIYPQI---RNNHPADPEA-M 127
            ..||.:||.  .||||||.||:|:.:|:.|||:|.|.||......:.|.|   ....|:|..| :
  Fly    73 CSYLADKYAPEGDDSLYPKDPEKRRLVDARLYYDCGHLFPRIRFIVEPVIYFGAGEVPSDRVAYL 137

  Fly   128 QKVDSAFGHLDTFLEDQEYVAGDCLTIADIALLASVSTFEV-VDFDIAQYPNVARWYENAKEVTP 191
            ||   |:..|:..|.:.:|:.||.|||||::.:|||||.|. ...:..|:|.:.:|.:..:.:..
  Fly   138 QK---AYDGLEHCLAEGDYLVGDKLTIADLSCIASVSTAEAFAPIEPDQFPRLVQWVKRIQALPY 199

  Fly   192 GWEENWDG----VQLIKKLVQERNE 212
            ..:.|.:|    |.|:|.|:.||.:
  Fly   200 YQKNNQEGLDMLVGLVKGLLAERQQ 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstD8	NP_524916.1	GstA	1..188	CDD:223698	80/190 (42%)
		GST_N_Delta_Epsilon	1..74	CDD:239343	34/69 (49%)
		GST_C_Delta_Epsilon	88..204	CDD:198287	40/124 (32%)
GstE11	NP_001286575.1	GstA	5..198	CDD:223698	80/192 (42%)
		GST_N_Delta_Epsilon	5..78	CDD:239343	34/69 (49%)
		GST_C_Delta_Epsilon	94..211	CDD:198287	38/119 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460274
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D118089at33392
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	11	10.800