DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstD8 and GstE6

DIOPT Version :9

Sequence 1:	NP_524916.1	Gene:	GstD8 / 48341	FlyBaseID:	FBgn0010044	Length:	212	Species:	Drosophila melanogaster
Sequence 2:	NP_611328.1	Gene:	GstE6 / 37111	FlyBaseID:	FBgn0063494	Length:	222	Species:	Drosophila melanogaster

Alignment Length:	207	Identity:	77/207 - (37%)
Similarity:	125/207 - (60%)	Gaps:	5/207 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 SAPCRSVIMTAKALGVDLNMKLLKVMDGEQLKPEFVKLNPQHCIPTLVDDGFSIWESRAILIYLV 73
            |.|.|:|.:|..||.:......:.::...||.||:::.||||.:|||.|||..||:|.||:.|||
  Fly    12 SPPVRAVKLTLAALNLTYEYVNVDIVARAQLSPEYLEKNPQHTVPTLEDDGHYIWDSHAIIAYLV 76

  Fly    74 EKYGADDSLYPSDPQKKAVVNQRLYFDMGTLFQSFVEAIYPQI--RNNHPADPEAMQKVDSAFGH 136
            .||...|:|||.||.|:|||:|||:|:.|.:|.:.:.:|...:  :.......|....:...:..
  Fly    77 SKYADSDALYPKDPLKRAVVDQRLHFESGVVFANGIRSISKSVLFQGQTKVPKERYDAIIEIYDF 141

  Fly   137 LDTFLEDQEYVAGDCLTIADIALLASVSTFEV-VDFDIAQYPNVARWYENAKEVTPGWEE-NWDG 199
            ::|||:.|:|:||:.|||||.:|::||::.|. |..|..:||.:..|.:..::: |.:|| |..|
  Fly   142 VETFLKGQDYIAGNQLTIADFSLVSSVASLEAFVALDTTKYPRIGAWIKKLEQL-PYYEEANGKG 205

  Fly   200 VQLIKKLVQERN 211
            |:.:..:.::.|
  Fly   206 VRQLVAIFKKTN 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstD8	NP_524916.1	GstA	1..188	CDD:223698	70/181 (39%)
		GST_N_Delta_Epsilon	1..74	CDD:239343	28/64 (44%)
		GST_C_Delta_Epsilon	88..204	CDD:198287	39/119 (33%)
GstE6	NP_611328.1	GstA	4..196	CDD:223698	70/184 (38%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	28/64 (44%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	39/118 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460272
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D118089at33392
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	11	10.800