Protein Alignment GstD8 and Clic2

DIOPT Version :10

• Sequence 1: NP_524916.1
• Gene: GstD8 / 48341
• FlyBaseID: FBgn0010044
• Length: 212
• Species: Drosophila melanogaster
• Sequence 2: NP_001009651.1
• Gene: Clic2 / 294141
• RGDID: 1306580
• Length: 245
• Species: Rattus norvegicus
• Alignment Length: 212
• Identity: 57/212 - (26%)
• Similarity: 83/212 - (39%)
• Gaps: 62/212 - (29%)

  Fly    12 CRSVIMTAKALGVDLNMKLLKVMDGEQLKPEFVK-----LNPQHCI--PTLVDDGFSIWESRAIL 69
            |:.:.|.....||..|:..:..    ..|||.:|     .||...|  ..|..|...|.|
  Rat    33 CQRLFMILWLKGVKFNVTTIDT----ARKPEELKDLAPGTNPPFLIYNKELKTDFIKIEE----- 88

  Fly    70 IYLVEKYGADDSLYPS-DPQKKAVVNQRLYFDMG-TLFQSFVEAIYPQIRNNHPADPEAMQKVDS 132
              .:||..|... ||. .|:.|.      .||:| .||..|  :.|  |:|   ...||.:..:.
  Rat    89 --FLEKTLAPPR-YPHLSPKYKE------SFDVGCNLFAKF--SAY--IKN---TQKEANKNFEK 137

  Fly   133 A----FGHLDTFL-------------EDQE-----YVAGDCLTIADIALLASVSTFEVV-----D 170
            :    |..||.:|             |::.     ::.||.||:||.:||..::..:|.     |
  Rat   138 SLLREFKRLDDYLNTPLLDEIDPDSTEERTLSRRLFLDGDQLTLADCSLLPKLNIIKVAAKKYRD 202

  Fly   171 FDI-AQYPNVARWYENA 186
            ||| |::..|.|:..||
  Rat   203 FDIPAEFSGVWRYLHNA 219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstD8	NP_524916.1	GST_N_Delta_Epsilon	1..74	CDD:239343	16/68 (24%)
		GST_C_Delta_Epsilon	88..204	CDD:198287	35/128 (27%)
Clic2	NP_001009651.1	Required for insertion into the membrane. /evidence=ECO:0000250	1..96		18/73 (25%)
		O-ClC	12..245	CDD:129941	57/212 (27%)
		G-site. /evidence=ECO:0000250|UniProtKB:O15247	30..33		57/212 (27%)