DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstD8 and Vars1

DIOPT Version :9

Sequence 1:	NP_524916.1	Gene:	GstD8 / 48341	FlyBaseID:	FBgn0010044	Length:	212	Species:	Drosophila melanogaster
Sequence 2:	NP_445744.1	Gene:	Vars1 / 25009	RGDID:	3950	Length:	1264	Species:	Rattus norvegicus

Alignment Length:	177	Identity:	44/177 - (24%)
Similarity:	69/177 - (38%)	Gaps:	36/177 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 PQHCIPTLVD--DGFSIWESRAI--LIYLVEKYGADDSLYPSDPQKKAVVNQRLYFDMGTLFQSF 108
            |...:|.|..  .|..:|.:.|:  |::.....|      |...:...:|.|.:.:....|..:.
  Rat    53 PPPRLPALEQGPGGLWVWGAPAVAQLLWPAGLGG------PGGSRAAVLVQQWVSYADTELTPAA 111

  Fly   109 VEAIYPQIRNNHPA-DPE-AMQKVDSAFGHLDTFLEDQEYVAGDCLTIADI-ALLASVSTFEVVD 170
            ..|..|.:....|. ||: |:..:..|...|:.:|....|:|||..|:||: |:.|.:..|..|.
  Rat   112 CGATLPALGLRGPGQDPQAALGALGKALNPLEEWLRLHTYLAGDAPTLADLAAVTALLLPFRYVL 176

  Fly   171 FDIAQ--YPNVARW-------------------YENAKEVT--PGWE 194
            ...|:  :.||.||                   |..|:.||  ||.|
  Rat   177 DPSARRIWGNVTRWFNTCVRQPEFRAVLGEVVLYSGARSVTQQPGSE 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstD8	NP_524916.1	GstA	1..188	CDD:223698	39/167 (23%)
		GST_N_Delta_Epsilon	1..74	CDD:239343	7/29 (24%)
		GST_C_Delta_Epsilon	88..204	CDD:198287	35/133 (26%)
Vars1	NP_445744.1	GstA	<56..203	CDD:223698	36/152 (24%)
		GST_C_family	92..213	CDD:295467	29/120 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	218..296		3/6 (50%)
		PTZ00419	282..1264	CDD:240411
		ValRS_core	335..938	CDD:185677
		'HIGH' region	344..354
		tRNA-synt_1_2	513..640	CDD:290334
		'KMSKS' region	862..866
		Anticodon_Ia_Val	938..1075	CDD:153416
		Val_tRNA-synt_C	1196..1258	CDD:287436
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810