DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstD8 and EEF1G

DIOPT Version :9

Sequence 1:	NP_524916.1	Gene:	GstD8 / 48341	FlyBaseID:	FBgn0010044	Length:	212	Species:	Drosophila melanogaster
Sequence 2:	NP_001395.1	Gene:	EEF1G / 1937	HGNCID:	3213	Length:	437	Species:	Homo sapiens

Alignment Length:	175	Identity:	46/175 - (26%)
Similarity:	85/175 - (48%)	Gaps:	13/175 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 PEFVKLNPQHCIPTLV-DDGFSIWESRAILIYLVEKYGADDSLYPSDPQKKAVVNQRLYFDMGTL 104
            |||::..|...:|... ||||.::||.||..|:     :::.|..|.|:..|.|.|.:.|....:
Human    47 PEFLRKFPAGKVPAFEGDDGFCVFESNAIAYYV-----SNEELRGSTPEAAAQVVQWVSFADSDI 106

  Fly   105 FQSFVEAIYPQI---RNNHPADPEAMQKVDSAFGHLDTFLEDQEYVAGDCLTIADIALLASVSTF 166
            .......::|.:   .:|..|...|.::|....|.||.:|:.:.::.|:.:|:|||.::.::...
Human   107 VPPASTWVFPTLGIMHHNKQATENAKEEVRRILGLLDAYLKTRTFLVGERVTLADITVVCTLLWL 171

  Fly   167 --EVVDFDIAQ-YPNVARWYENAKEVTPGWEENWDGVQLIKKLVQ 208
              :|::....| :||..||:..... .|.:......|:|.:|:.|
Human   172 YKQVLEPSFRQAFPNTNRWFLTCIN-QPQFRAVLGEVKLCEKMAQ 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstD8	NP_524916.1	GstA	1..188	CDD:223698	41/153 (27%)
		GST_N_Delta_Epsilon	1..74	CDD:239343	14/33 (42%)
		GST_C_Delta_Epsilon	88..204	CDD:198287	27/121 (22%)
EEF1G	NP_001395.1	GST_N_EF1Bgamma	4..82	CDD:239342	14/39 (36%)
		GST_C_EF1Bgamma_like	91..213	CDD:198290	27/122 (22%)
		tolA	<212..>278	CDD:236545	2/4 (50%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	221..268
		EF1G	277..381	CDD:395522
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810