Protein Alignment GstD7 and MARS1

DIOPT Version :10

• Sequence 1: NP_525114.1
• Gene: GstD7 / 48340
• FlyBaseID: FBgn0010043
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: NP_004981.2
• Gene: MARS1 / 4141
• HGNCID: 6898
• Length: 900
• Species: Homo sapiens
• Alignment Length: 261
• Identity: 55/261 - (21%)
• Similarity: 93/261 - (35%)
• Gaps: 96/261 - (36%)

  Fly    11 MAPASRA---IQMVAKALGLELNSKLINTMEGDQLKPEFVRINPQHTIPTL-VDNGFVIWESRAI 71
            :|.|.||   .:::...:|.|           |.:.|...|  |:  :|.| :|:|..::.:.||
Human    16 LAAAGRARGRAEVLISTVGPE-----------DCVVPFLTR--PK--VPVLQLDSGNYLFSTSAI 65

  Fly    72 AVY--LVEKYGKPDSPLYPNDPQKRALINQRLYFDMGTLYDALTKYFFLIFRTGKFGDQEALDKV 134
            ..|  |:..:.:.|            |.||.|.::...|..||:...:.:...||.| ::.|..|
Human    66 CRYFFLLSGWEQDD------------LTNQWLEWEATELQPALSAALYYLVVQGKKG-EDVLGSV 117

  Fly   135 NSAFGFLNTFLEGQD--FVAGSQLTVADIVILATVSTV---------------EWFSFDLSKFPN 182
            ..|...::..|..|:  |:||...::||||:...:..:               .||. .||....
Human   118 RRALTHIDHSLSRQNCPFLAGETESLADIVLWGALYPLLQDPAYLPEELSALHSWFQ-TLSTQEP 181

  Fly   183 VER----------------WLKNAPKVTP----------------------------GWEQNLES 203
            .:|                :|:..|:.:|                            .||:.|||
Human   182 CQRAAETVLKQQGVLALRPYLQKQPQPSPAEGRAVTNEPEEEELATLSEEEIAMAVTAWEKGLES 246

  Fly   204 L 204
            |
Human   247 L 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstD7	NP_525114.1	GST_N_Delta_Epsilon	4..77	CDD:239343	18/71 (25%)
		GST_C_Delta_Epsilon	92..206	CDD:198287	36/174 (21%)
MARS1	NP_004981.2	GST_N_5	1..74	CDD:436537	18/72 (25%)
		GST_C_MetRS_N	77..179	CDD:198340	27/115 (23%)
		PLN02610	251..893	CDD:215329
		'HIGH' region	273..283
		'KMSKS' region	593..597