DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstD7 and GstE6

DIOPT Version :9

Sequence 1:	NP_525114.1	Gene:	GstD7 / 48340	FlyBaseID:	FBgn0010043	Length:	224	Species:	Drosophila melanogaster
Sequence 2:	NP_611328.1	Gene:	GstE6 / 37111	FlyBaseID:	FBgn0063494	Length:	222	Species:	Drosophila melanogaster

Alignment Length:	211	Identity:	77/211 - (36%)
Similarity:	129/211 - (61%)	Gaps:	8/211 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPNLDLYNFPMAPASRAIQMVAKALGLELNSKLINTMEGDQLKPEFVRINPQHTIPTLVDNGFVI 65
            |..|.||....:|..||:::...||.|......::.:...||.||::..|||||:|||.|:|..|
  Fly     1 MVKLTLYGLDPSPPVRAVKLTLAALNLTYEYVNVDIVARAQLSPEYLEKNPQHTVPTLEDDGHYI 65

  Fly    66 WESRAIAVYLVEKYGKPDSPLYPNDPQKRALINQRLYFDMGTLY----DALTKYFFLIFRTGKFG 126
            |:|.||..|||.||...|: |||.||.|||:::|||:|:.|.::    .:::|  .::|:.....
  Fly    66 WDSHAIIAYLVSKYADSDA-LYPKDPLKRAVVDQRLHFESGVVFANGIRSISK--SVLFQGQTKV 127

  Fly   127 DQEALDKVNSAFGFLNTFLEGQDFVAGSQLTVADIVILATVSTVEWF-SFDLSKFPNVERWLKNA 190
            .:|..|.:...:.|:.|||:|||::||:|||:||..::::|:::|.| :.|.:|:|.:..|:|..
  Fly   128 PKERYDAIIEIYDFVETFLKGQDYIAGNQLTIADFSLVSSVASLEAFVALDTTKYPRIGAWIKKL 192

  Fly   191 PKVTPGWEQNLESLQQ 206
            .::....|.|.:.::|
  Fly   193 EQLPYYEEANGKGVRQ 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstD7	NP_525114.1	GST_N_Delta_Epsilon	4..77	CDD:239343	30/72 (42%)
		GstA	6..188	CDD:223698	71/186 (38%)
		GST_C_Delta_Epsilon	92..206	CDD:198287	36/118 (31%)
GstE6	NP_611328.1	GstA	4..196	CDD:223698	73/194 (38%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	30/72 (42%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	37/120 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460337
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1231780at2759
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	11	10.800