DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstD7 and GstE4

DIOPT Version :9

Sequence 1:	NP_525114.1	Gene:	GstD7 / 48340	FlyBaseID:	FBgn0010043	Length:	224	Species:	Drosophila melanogaster
Sequence 2:	NP_611326.1	Gene:	GstE4 / 37109	FlyBaseID:	FBgn0063496	Length:	222	Species:	Drosophila melanogaster

Alignment Length:	229	Identity:	77/229 - (33%)
Similarity:	124/229 - (54%)	Gaps:	22/229 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPNLDLYNFPMAPASRAIQMVAKALGLELNSKLINTMEGDQLKPEFVRINPQHTIPTLVDNGFVI 65
            |..:.||....:|.:||..:..|||.|......:|..|.:....:|.:.|||||:|.|.|:...|
  Fly     1 MGKISLYGLDASPPTRACLLTLKALDLPFEFVFVNLFEKENFSEDFSKKNPQHTVPLLQDDDACI 65

  Fly    66 WESRAIAVYLVEKYGKPDSPLYPNDPQKRALINQRLYFDMGTLYDA----LTKYFFLIFRTGKFG 126
            |:|.||..||||||. |...|||.|..:||.::|.::|:.|.::::    ||:.  ::|    ||
  Fly    66 WDSHAIMAYLVEKYA-PSDELYPKDLLQRAKVDQLMHFESGVIFESALRRLTRP--VLF----FG 123

  Fly   127 D----QEALDKVNSAFGFLNTFLEGQDFVAGSQLTVADIVILATVSTVEWF-SFDLSKFPNVERW 186
            :    :..:|.:...:.|:.|||:..|||||.|||:||..|::|::::..| ..|.:|:|.:..|
  Fly   124 EPTLPRNQVDHILQVYDFVETFLDDHDFVAGDQLTIADFSIVSTITSIGVFLELDPAKYPKIAAW 188

  Fly   187 LKNAPKVTPGWEQNLESLQQGKKFLQDLQAAKEK 220
            |:.. |..|.:|:     ..||...|.::..:.|
  Fly   189 LERL-KELPYYEE-----ANGKGAAQFVELLRSK 216

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstD7	NP_525114.1	GST_N_Delta_Epsilon	4..77	CDD:239343	27/72 (38%)
		GstA	6..188	CDD:223698	68/190 (36%)
		GST_C_Delta_Epsilon	92..206	CDD:198287	36/122 (30%)
GstE4	NP_611326.1	GST_N_Delta_Epsilon	4..77	CDD:239343	27/72 (38%)
		GstA	6..196	CDD:223698	70/197 (36%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	38/129 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460329
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1231780at2759
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	11	10.800