Protein Alignment GstD7 and GSTA4

DIOPT Version :10

• Sequence 1: NP_525114.1
• Gene: GstD7 / 48340
• FlyBaseID: FBgn0010043
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: NP_001503.1
• Gene: GSTA4 / 2941
• HGNCID: 4629
• Length: 222
• Species: Homo sapiens
• Alignment Length: 211
• Identity: 51/211 - (24%)
• Similarity: 96/211 - (45%)
• Gaps: 54/211 - (25%)

  Fly    17 AIQMVAKALGLELNSKLINTME-------GDQLKPEFVRINPQHTIPTLVDNGFVIWESRAIAVY 74
            :::.|..|.|:|.:.:.:.|.|       |:.|..:        .:|.:..:|..:.::|:|..|
Human    18 SVRWVLAAAGVEFDEEFLETKEQLYKLQDGNHLLFQ--------QVPMVEIDGMKLVQTRSILHY 74

  Fly    75 LVEKYGKPDSPLYPNDPQKRALINQRLYFDMGT--LYDALTKYFFLIFRTGKFGDQEALDKVNSA 137
            :.:|:.     |:..:.::|.||:  :|.: ||  |.:.|..:.||     |..||:. :.||.|
Human    75 IADKHN-----LFGKNLKERTLID--MYVE-GTLDLLELLIMHPFL-----KPDDQQK-EVVNMA 125

  Fly   138 -------FGFLNTFL--EGQDFVAGSQLTVADIVILATVSTVE--------------WFSFDLSK 179
                   |......|  .||.|:.|:||::||:::|.|:..:|              .::..||.
Human   126 QKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPFLQEYTVKLSN 190

  Fly   180 FPNVERWLKNAPKVTP 195
            .|.::|:|:...|..|
Human   191 IPTIKRFLEPGSKKKP 206

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstD7	NP_525114.1	GST_N_Delta_Epsilon	4..77	CDD:239343	13/66 (20%)
		GST_C_Delta_Epsilon	92..206	CDD:198287	36/129 (28%)
GSTA4	NP_001503.1	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold	4..82	CDD:469754	14/76 (18%)
		GST_C_Alpha	86..220	CDD:198317	36/130 (28%)