Protein Alignment GstD7 and CLIC4

DIOPT Version :10

• Sequence 1: NP_525114.1
• Gene: GstD7 / 48340
• FlyBaseID: FBgn0010043
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: NP_039234.1
• Gene: CLIC4 / 25932
• HGNCID: 13518
• Length: 253
• Species: Homo sapiens
• Alignment Length: 170
• Identity: 34/170 - (20%)
• Similarity: 75/170 - (44%)
• Gaps: 44/170 - (25%)

  Fly    31 SKLINTMEGDQLKPEFVRINPQHTIPTLVDNGFVIWESRAIAVYLVEKYGKPDSPLYPNDPQKRA 95
            :|:...:|.....|::::::|:|  |.....|..|:..  .:.|:  |..:|::    |:..:|.
Human    89 NKIEEFLEEVLCPPKYLKLSPKH--PESNTAGMDIFAK--FSAYI--KNSRPEA----NEALERG 143

  Fly    96 LIN--QRL--YFDMGTLYDALTKYFFLIFRTGKFGDQEALDKVNSAFGFLNTFLEGQDFVAGSQL 156
            |:.  |:|  |.: ..|.|.:              |:.:::.:.         ...:.|:.|:::
Human   144 LLKTLQKLDEYLN-SPLPDEI--------------DENSMEDIK---------FSTRKFLDGNEM 184

  Fly   157 TVADIVILATVSTV-----EWFSFDLSK-FPNVERWLKNA 190
            |:||..:|..:..|     ::.:||:.| ...:.|:|.||
Human   185 TLADCNLLPKLHIVKVVAKKYRNFDIPKEMTGIWRYLTNA 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstD7	NP_525114.1	GST_N_Delta_Epsilon	4..77	CDD:239343	9/45 (20%)
		GST_C_Delta_Epsilon	92..206	CDD:198287	22/109 (20%)
CLIC4	NP_039234.1	Required for insertion into the membrane. /evidence=ECO:0000305	2..101		2/11 (18%)
		O-ClC	17..252	CDD:129941	34/170 (20%)
		G-site. /evidence=ECO:0000250|UniProtKB:Q9Z0W7	35..38