DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstD7 and Gdap1

DIOPT Version :9

Sequence 1:	NP_525114.1	Gene:	GstD7 / 48340	FlyBaseID:	FBgn0010043	Length:	224	Species:	Drosophila melanogaster
Sequence 2:	NP_034397.1	Gene:	Gdap1 / 14545	MGIID:	1338002	Length:	358	Species:	Mus musculus

Alignment Length:	222	Identity:	43/222 - (19%)
Similarity:	87/222 - (39%)	Gaps:	52/222 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 NLDLYNFPMAPASRAIQMVAKALGLELNSKLINTMEGDQLKPEFVRINPQHTIPTLVDNGFVIWE 67
            :|.||::..:.:|:.:::|.....|:.....::....:..:|.|:|:|....:|.||....:|.|
Mouse    25 HLILYHWTHSFSSQKVRLVIAEKALKCEEHDVSLPLSEHNEPWFMRLNSAGEVPVLVHGENIICE 89

  Fly    68 SRAIAVYLVEKYGKPDSPLYPNDPQKRALINQRLYFDMGTLYDALTKYFFLIFRTGKFGDQEALD 132
            :..|..||.:.:....:|              ||..|.|::|....:::           :|.||
Mouse    90 ATQIIDYLEQTFLDERTP--------------RLMPDEGSMYYPRVQHY-----------RELLD 129

  Fly   133 KVNSAFGFLNTFLEGQDFVAGSQLTVADIVILATVSTVEWFSFDLSKFPNVERWLKNAPKVTPGW 197
            .:.     ::.:..|  .:...:|||..::.....:.:.      |:..|.|..||...:..|.
Mouse   130 SLP-----MDAYTHG--CILHPELTVDSMIPAYATTRIR------SQIGNTESELKKLAEENPD- 180

  Fly   198 EQNLESLQQGKKFLQDLQAAKEKEVKA 224
                         ||:...||:|.:|:
Mouse   181 -------------LQEAYIAKQKRLKS 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstD7	NP_525114.1	GST_N_Delta_Epsilon	4..77	CDD:239343	18/72 (25%)
		GstA	6..188	CDD:223698	33/181 (18%)
		GST_C_Delta_Epsilon	92..206	CDD:198287	18/113 (16%)
Gdap1	NP_034397.1	GST_N_GDAP1	26..98	CDD:239350	17/71 (24%)
		GST_C_GDAP1	179..289	CDD:198336	7/30 (23%)
		Required for mitochondrial localization. /evidence=ECO:0000250	320..358
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844787
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840