Protein Alignment GstD7 and CLIC2

DIOPT Version :9

• Sequence 1: NP_525114.1
• Gene: GstD7 / 48340
• FlyBaseID: FBgn0010043
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: NP_001280.3
• Gene: CLIC2 / 1193
• HGNCID: 2063
• Length: 247
• Species: Homo sapiens
• Alignment Length: 223
• Identity: 50/223 - (22%)
• Similarity: 89/223 - (39%)
• Gaps: 49/223 - (21%)

  Fly     2 PNLDLY--------NFPMAPASRAIQMVAKALGLELNSKLIN-TMEGDQLKPEFVRINPQHTIPT 57
            |.::|:        :....|..:.:.|:....|::.|...:: |.:.::||......||    |.
Human    12 PEIELFVKAGSDGESIGNCPFCQRLFMILWLKGVKFNVTTVDMTRKPEELKDLAPGTNP----PF 72

  Fly    58 LVDNGFVIWESRAIAVYLVEKYGKPDSP-LYPNDPQKRALINQRLYFDMGTLYDALTKYFFLIFR 121
            ||.|..:..:...|..:|.:....|..| |.|...:.         ||:|.  :...|:...|..
Human    73 LVYNKELKTDFIKIEEFLEQTLAPPRYPHLSPKYKES---------FDVGC--NLFAKFSAYIKN 126

  Fly   122 TGKFG----DQEALDKVNSAFGFLNT-FLEGQD-------------FVAGSQLTVADIVILATVS 168
            |.|..    ::..|.:......:||| .|:..|             |:.|.|||:||..:|..::
Human   127 TQKEANKNFEKSLLKEFKRLDDYLNTPLLDEIDPDSAEEPPVSRRLFLDGDQLTLADCSLLPKLN 191

  Fly   169 TV-----EWFSFDL-SKFPNVERWLKNA 190
            .:     ::..||: ::|..|.|:|.||
Human   192 IIKVAAKKYRDFDIPAEFSGVWRYLHNA 219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstD7	NP_525114.1	GST_N_Delta_Epsilon	4..77	CDD:239343	16/81 (20%)
		GstA	6..188	CDD:223698	46/215 (21%)
		GST_C_Delta_Epsilon	92..206	CDD:198287	29/123 (24%)
CLIC2	NP_001280.3	Required for insertion into the membrane. /evidence=ECO:0000250	1..96		17/87 (20%)
		N-terminal	1..94		17/85 (20%)
		O-ClC	12..245	CDD:129941	50/223 (22%)
		Joint loop	95..106		4/10 (40%)
		C-terminal	107..247		29/124 (23%)
		Foot loop	151..171		4/19 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154399
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930