Protein Alignment GstD6 and Clic2

DIOPT Version :10

• Sequence 1: NP_524915.1
• Gene: GstD6 / 48339
• FlyBaseID: FBgn0010042
• Length: 215
• Species: Drosophila melanogaster
• Sequence 2: NP_001009651.1
• Gene: Clic2 / 294141
• RGDID: 1306580
• Length: 245
• Species: Rattus norvegicus
• Alignment Length: 222
• Identity: 46/222 - (20%)
• Similarity: 91/222 - (40%)
• Gaps: 52/222 - (23%)

  Fly     1 MDLYNMSGS--------PSTRAVMMTAKAVGVEFNSIQVNTF-VGEQLEPWFVKINPQHTIPTLV 56
            ::|:..:||        |..:.:.|.....||:||...::|. ..|:|:......||.
  Rat    14 IELFVKAGSDGESIGNCPFCQRLFMILWLKGVKFNVTTIDTARKPEELKDLAPGTNPP------- 71

  Fly    57 DNLFVIWETRAIVVYL-VEQYGKDDSLYPKDPQKQALINQRLYFDMG-TLYDGIAKYFFPLLRTG 119
               |:|:.......:: :|::.:.....|:.|.......:.  ||:| .|:...:.|    ::..
  Rat    72 ---FLIYNKELKTDFIKIEEFLEKTLAPPRYPHLSPKYKES--FDVGCNLFAKFSAY----IKNT 127

  Fly   120 KPGTQENLEK-LNAAFDLLNNFL----------DGQD--------YVAGNQLSVADIVILATVST 165
            :....:|.|| |...|..|:::|          |..:        ::.|:||::||..:|..::.
  Rat   128 QKEANKNFEKSLLREFKRLDDYLNTPLLDEIDPDSTEERTLSRRLFLDGDQLTLADCSLLPKLNI 192

  Fly   166 TEMV-----DFDL-KKFPNVDRWYKNA 186
            .::.     |||: .:|..|.|:..||
  Rat   193 IKVAAKKYRDFDIPAEFSGVWRYLHNA 219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstD6	NP_524915.1	GST_N_Delta_Epsilon	1..74	CDD:239343	16/82 (20%)
		GST_C_Delta_Epsilon	88..204	CDD:198287	27/125 (22%)
Clic2	NP_001009651.1	Required for insertion into the membrane. /evidence=ECO:0000250	1..96		17/91 (19%)
		O-ClC	12..245	CDD:129941	46/222 (21%)
		G-site. /evidence=ECO:0000250|UniProtKB:O15247	30..33		1/2 (50%)