Protein Alignment GstD6 and CLIC4

DIOPT Version :10

• Sequence 1: NP_524915.1
• Gene: GstD6 / 48339
• FlyBaseID: FBgn0010042
• Length: 215
• Species: Drosophila melanogaster
• Sequence 2: NP_039234.1
• Gene: CLIC4 / 25932
• HGNCID: 13518
• Length: 253
• Species: Homo sapiens
• Alignment Length: 207
• Identity: 42/207 - (20%)
• Similarity: 85/207 - (41%)
• Gaps: 69/207 - (33%)

  Fly     2 DLYNMSGSPSTRAVMMTAKA-VGVEFNSIQVNTFVGEQL-EPWFVKINPQHTIPTLVDNLFVIWE 64
            ||.|:  :|.|....:|..: |..:.|.|:  .|:.|.| .|.::|::|:|.            |
Human    65 DLQNL--APGTHPPFITFNSEVKTDVNKIE--EFLEEVLCPPKYLKLSPKHP------------E 113

  Fly    65 TRAIVVYLVEQYGKDDSLYPKDPQKQALINQRLYFDMGTLYDGIAKYFFPLLRTGKPGTQENLEK 129
            :....:.:..::    |.|.|:.:.:|  |:.|                      :.|..:.|:|
Human   114 SNTAGMDIFAKF----SAYIKNSRPEA--NEAL----------------------ERGLLKTLQK 150

  Fly   130 LNAAFDLLNNFLDGQ--------------DYVAGNQLSVADIVILATVSTTEMV-----DFDL-K 174
            |:   :.||:.|..:              .::.||::::||..:|..:...::|     :||: |
Human   151 LD---EYLNSPLPDEIDENSMEDIKFSTRKFLDGNEMTLADCNLLPKLHIVKVVAKKYRNFDIPK 212

  Fly   175 KFPNVDRWYKNA 186
            :...:.|:..||
Human   213 EMTGIWRYLTNA 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstD6	NP_524915.1	GST_N_Delta_Epsilon	1..74	CDD:239343	17/73 (23%)
		GST_C_Delta_Epsilon	88..204	CDD:198287	22/119 (18%)
CLIC4	NP_039234.1	Required for insertion into the membrane. /evidence=ECO:0000305	2..101		12/39 (31%)
		O-ClC	17..252	CDD:129941	42/207 (20%)
		G-site. /evidence=ECO:0000250|UniProtKB:Q9Z0W7	35..38