DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstD6 and gst2

DIOPT Version :9

Sequence 1:	NP_524915.1	Gene:	GstD6 / 48339	FlyBaseID:	FBgn0010042	Length:	215	Species:	Drosophila melanogaster
Sequence 2:	NP_588517.1	Gene:	gst2 / 2539601	PomBaseID:	SPCC965.07c	Length:	230	Species:	Schizosaccharomyces pombe

Alignment Length:	227	Identity:	61/227 - (26%)
Similarity:	102/227 - (44%)	Gaps:	37/227 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LYNMSGSPSTRAVMMTAKAVGVEFNSIQVNTFVGEQLEPWFVKINPQHTIPTLVD---NLFVIWE 64
            ||:.:|.|:...|::..|.:.:.:..|..:...|||.....:.:||...:|||||   |.:.|||
pombe     6 LYSHAGGPNPWKVVLALKELNLSYEQIFYDFQKGEQKCKEHLALNPNGRVPTLVDHKNNDYTIWE 70

  Fly    65 TRAIVVYLVEQYGKDD--SLYPKDPQKQALINQRLYFD---MGTLYDGIAKYF-----FPLLRTG 119
            :.||::||.::|..|.  ||...||:...|| |.|:|.   .|.:: |.|.:|     .|::
pombe    71 SDAILIYLADKYDTDRKISLSFDDPEYYKLI-QYLFFQASGQGVIW-GQAGWFNFFHHEPVV--- 130

  Fly   120 KPGTQENLEKLNAAFDLLNNFLDGQDYVAGNQLSVADIVIL------------ATVSTTEMV--- 169
             ........::.....:|.:.|..:||:..|:.::||:..:            ...|..|.|
pombe   131 -SAVTRYRNEIKRVLGVLEDILKDRDYLVANKYTIADLSFIPWNYNLGGLFGEGKFSFKEEVPQL 194

  Fly   170 DFDLKKFPNVDRWYKN--AQKVTPGWDENLAR 199
            ||: |:||....|.:.  |:.......|.||:
pombe   195 DFE-KEFPKAYAWNQRLLARPAVKATFEELAK 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstD6	NP_524915.1	GST_N_Delta_Epsilon	1..74	CDD:239343	25/73 (34%)
		PLN02395	11..208	CDD:166036	57/219 (26%)
		GST_C_Delta_Epsilon	88..204	CDD:198287	30/137 (22%)
gst2	NP_588517.1	GST_N_Ure2p_like	4..84	CDD:239346	26/77 (34%)
		GstA	5..226	CDD:223698	61/227 (27%)
		GST_C_Ure2p	96..219	CDD:198326	27/129 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	54	1.000	Domainoid score	I3221
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	80	1.000	Inparanoid score	I1854
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm9258
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
TreeFam	1	0.960	-	-
	10	9.720