Protein Alignment GstD5 and AIMP2

DIOPT Version :10

• Sequence 1: NP_524914.3
• Gene: GstD5 / 48338
• FlyBaseID: FBgn0010041
• Length: 216
• Species: Drosophila melanogaster
• Sequence 2: NP_006294.2
• Gene: AIMP2 / 7965
• HGNCID: 20609
• Length: 320
• Species: Homo sapiens
• Alignment Length: 217
• Identity: 42/217 - (19%)
• Similarity: 83/217 - (38%)
• Gaps: 63/217 - (29%)

  Fly    13 RTVIMVAKALGVKLNMKLLNTLEKDQLKPEFVKLNPQHTIPTLVDNGFSIWESRAIAVYLVEKYG 77
            :.:::.|......|::.:|:.|    |...|..|:..||..::          :::...|::.:|
Human   120 KDIVINANPASPPLSLLVLHRL----LCEHFRVLSTVHTHSSV----------KSVPENLLKCFG 170

  Fly    78 KDDTLFPKD-------------PKKQALVNQRLYFDMGTL-----YDSFAKYYYPLF---HTG-- 119
            :.:...|:.             ||.|      :.|.:.|:     ..:.|::.:.||   |..
Human   171 EQNKKQPRQDYQLGFTLIWKNVPKTQ------MKFSIQTMCPIEGEGNIARFLFSLFGQKHNAVN 229

  Fly   120 ---------------KPGSDEDFKKIESSFEYLNIFLEGQNYVAGDHLTVADIAILSTVSTFEIF 169
                           |.||.   |:..:.|..:|..|....::||:.|||||:.:.|.:.  :|.
Human   230 ATLIDSWVDIAIFQLKEGSS---KEKAAVFRSMNSALGKSPWLAGNELTVADVVLWSVLQ--QIG 289

  Fly   170 DFDLNKYPNVARWYANAKKVTP 191
            ...:....||.||..:.:.:.|
Human   290 GCSVTVPANVQRWMRSCENLAP 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstD5	NP_524914.3	GST_N_Delta_Epsilon	1..74	CDD:239343	10/60 (17%)
		GST_C_Delta_Epsilon	88..204	CDD:198287	29/129 (22%)
AIMP2	NP_006294.2	AIMP2_LysRS_bd	1..44	CDD:465269
		Interaction with PRKN. /evidence=ECO:0000269|PubMed:16135753	82..162		9/55 (16%)
		Thioredoxin_16	117..208	CDD:436585	17/107 (16%)
		Interaction with TP53. /evidence=ECO:0000269|PubMed:18695251	162..225		11/68 (16%)
		GST_C_AIMP2	214..309	CDD:198309	24/99 (24%)