DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment GstD5 and GDAP1

DIOPT Version :9

Sequence 1:NP_524914.3 Gene:GstD5 / 48338 FlyBaseID:FBgn0010041 Length:216 Species:Drosophila melanogaster
Sequence 2:NP_061845.2 Gene:GDAP1 / 54332 HGNCID:15968 Length:358 Species:Homo sapiens


Alignment Length:251 Identity:47/251 - (18%)
Similarity:87/251 - (34%) Gaps:84/251 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly    15 VIMVAKALGVKLNMKLLNTLEKDQLKPEFVKLNPQHTIPTLVDNGFSIWESRAIAVYLVEKYGKD 79
            :::..|||..:.:...|...|.::  |.|::||....:|.|:.....|.|:..|..||.:.:..:
Human    42 LVIAEKALKCEEHDVSLPLSEHNE--PWFMRLNSTGEVPVLIHGENIICEATQIIDYLEQTFLDE 104

  Fly    80 DTLFPK-DPKKQALVNQRL--YFDMGTLYDSFAKYYY----------------PLFHTGK----- 120
            .|  |: .|.|:::...|:  |.:   |.||.....|                |.:.|.:     
Human   105 RT--PRLMPDKESMYYPRVQHYRE---LLDSLPMDAYTHGCILHPELTVDSMIPAYATTRIRSQI 164

  Fly   121 PGSDEDFKKI------------------------ESSFEYLNIFL-------------------- 141
            ..::.:.||:                        ..:.:||...|                    
Human   165 GNTESELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVKYLKKILDELEKVLDQVETELQRRNEE 229

  Fly   142 ---EGQN-YVAGDHLTVADIAILSTVSTFEIFDF-----DLNKYPNVARWYANAKK 188
               |||. ::.|:..|:||:::..|:...:...|     ...|.||:..:|....|
Human   230 TPEEGQQPWLCGESFTLADVSLAVTLHRLKFLGFARRNWGNGKRPNLETYYERVLK 285

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GstD5NP_524914.3 GstA 1..184 CDD:223698 45/245 (18%)
GST_N_Delta_Epsilon 1..74 CDD:239343 16/58 (28%)
GST_C_Delta_Epsilon 88..204 CDD:198287 28/177 (16%)
GDAP1NP_061845.2 GST_N_GDAP1 26..98 CDD:239350 15/57 (26%)
GST_C_GDAP1 179..289 CDD:198336 17/107 (16%)
Required for mitochondrial localization 320..358
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165154501
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.930

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