DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstD5 and GstE11

DIOPT Version :9

Sequence 1:	NP_524914.3	Gene:	GstD5 / 48338	FlyBaseID:	FBgn0010041	Length:	216	Species:	Drosophila melanogaster
Sequence 2:	NP_001286575.1	Gene:	GstE11 / 37128	FlyBaseID:	FBgn0034354	Length:	225	Species:	Drosophila melanogaster

Alignment Length:	218	Identity:	77/218 - (35%)
Similarity:	129/218 - (59%)	Gaps:	12/218 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 YYSPRGSGCRTVIMVAKALGVKLNMKLLNTLEKDQLKPEFVKLNPQHTIPTLVDNGFSIWESRAI 68
            ||:||...||.|::.|.|||::|:::|:|....:....||:|||.|||||.|.|||..:.:|..|
  Fly     8 YYAPRSPPCRAVLLTAAALGLELDLRLVNVKAGEHKSAEFLKLNAQHTIPVLDDNGTIVSDSHII 72

  Fly    69 AVYLVEKYGK--DDTLFPKDPKKQALVNQRLYFDMGTLYDSFAKYYYPL--FHTGKPGSDEDFKK 129
            ..||.:||..  ||:|:||||:|:.||:.|||:|.|.|:........|:  |..|:..||. ...
  Fly    73 CSYLADKYAPEGDDSLYPKDPEKRRLVDARLYYDCGHLFPRIRFIVEPVIYFGAGEVPSDR-VAY 136

  Fly   130 IESSFEYLNIFLEGQNYVAGDHLTVADIAILSTVSTFEIF-DFDLNKYPNVARWYANAKKVTPGW 193
            ::.:::.|...|...:|:.||.||:||::.:::|||.|.| ..:.:::|.:.:|....:.: |.:
  Fly   137 LQKAYDGLEHCLAEGDYLVGDKLTIADLSCIASVSTAEAFAPIEPDQFPRLVQWVKRIQAL-PYY 200

  Fly   194 EENWKGAVEL-----KGVFDARQ 211
            ::|.:..:::     ||:...||
  Fly   201 QKNNQEGLDMLVGLVKGLLAERQ 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstD5	NP_524914.3	GstA	1..184	CDD:223698	71/184 (39%)
		GST_N_Delta_Epsilon	1..74	CDD:239343	32/69 (46%)
		GST_C_Delta_Epsilon	88..204	CDD:198287	32/123 (26%)
GstE11	NP_001286575.1	GstA	5..198	CDD:223698	71/191 (37%)
		GST_N_Delta_Epsilon	5..78	CDD:239343	32/69 (46%)
		GST_C_Delta_Epsilon	94..211	CDD:198287	32/118 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460235
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1231780at2759
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	11	10.800