DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstD5 and GSTZ1

DIOPT Version :9

Sequence 1:	NP_524914.3	Gene:	GstD5 / 48338	FlyBaseID:	FBgn0010041	Length:	216	Species:	Drosophila melanogaster
Sequence 2:	NP_001350632.1	Gene:	GSTZ1 / 2954	HGNCID:	4643	Length:	217	Species:	Homo sapiens

Alignment Length:	189	Identity:	58/189 - (30%)
Similarity:	83/189 - (43%)	Gaps:	23/189 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 YSPRGSGCRTVIMVAKAL-GVKLNMKLLNTLEKD---QLKPEFVKLNPQHTIPTLVDNGFSIWES 65
            ||...|.|...:.:|.|| |:......:| |.||   |...:|..|||...:|||..:|.:|.:|
Human    10 YSYFRSSCSWRVRIALALKGIDYETVPIN-LIKDGGQQFSKDFQALNPMKQVPTLKIDGITIHQS 73

  Fly    66 RAIAVYLVEKYGKDDTLFPKDPKKQALVNQRLYFDMGTLYDSFAKYYYPLFHTG---KPGSDEDF 127
            .||..|| |:......|.|:||||:|.|..        :.|..|....||.:..   :.|.:...
Human    74 LAIIEYL-EEMRPTPRLLPQDPKKRASVRM--------ISDLIAGGIQPLQNLSVLKQVGEEMQL 129

  Fly   128 ----KKIESSFEYLNIFLEGQN--YVAGDHLTVADIAILSTVSTFEIFDFDLNKYPNVA 180
                ..|...|..|...|:...  |..||.:|:||:.::..|:..|.|..||..||.::
Human   130 TWAQNAITCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAERFKVDLTPYPTIS 188

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstD5	NP_524914.3	GstA	1..184	CDD:223698	58/189 (31%)
		GST_N_Delta_Epsilon	1..74	CDD:239343	27/72 (38%)
		GST_C_Delta_Epsilon	88..204	CDD:198287	26/102 (25%)
GSTZ1	NP_001350632.1	maiA	8..212	CDD:273527	58/189 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810