DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment GstD5 and CLIC4

DIOPT Version :9

Sequence 1:NP_524914.3 Gene:GstD5 / 48338 FlyBaseID:FBgn0010041 Length:216 Species:Drosophila melanogaster
Sequence 2:NP_039234.1 Gene:CLIC4 / 25932 HGNCID:13518 Length:253 Species:Homo sapiens


Alignment Length:182 Identity:35/182 - (19%)
Similarity:67/182 - (36%) Gaps:70/182 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly    29 KLLNTLEKDQLKPEFVKLNPQHTIPTLVDNGFSIWESRAIAVYLVEKYGKDDTLFPKDPKKQALV 93
            |:...||:....|:::||:|:|.            ||....:.:..|:    :.:.|:.:.:|  
Human    90 KIEEFLEEVLCPPKYLKLSPKHP------------ESNTAGMDIFAKF----SAYIKNSRPEA-- 136

  Fly    94 NQRLYFDMGTLYDSFAKYYYPLFHTGKPGSDEDFKKIESSFEYLN--------------IFLEGQ 144
            |:.|  :.|.|                       |.::...||||              |....:
Human   137 NEAL--ERGLL-----------------------KTLQKLDEYLNSPLPDEIDENSMEDIKFSTR 176

  Fly   145 NYVAGDHLTVADIAILSTVSTFEIFDFDLNKYPNVARWYAN---AKKVTPGW 193
            .::.|:.:|:||..:|..:...::          ||:.|.|   .|::|..|
Human   177 KFLDGNEMTLADCNLLPKLHIVKV----------VAKKYRNFDIPKEMTGIW 218

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GstD5NP_524914.3 GstA 1..184 CDD:223698 30/168 (18%)
GST_N_Delta_Epsilon 1..74 CDD:239343 10/44 (23%)
GST_C_Delta_Epsilon 88..204 CDD:198287 23/123 (19%)
CLIC4NP_039234.1 Required for insertion into the membrane. /evidence=ECO:0000305 2..101 3/10 (30%)
O-ClC 17..252 CDD:129941 35/182 (19%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165154223
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.930

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