DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstD5 and GstE9

DIOPT Version :9

Sequence 1:	NP_524914.3	Gene:	GstD5 / 48338	FlyBaseID:	FBgn0010041	Length:	216	Species:	Drosophila melanogaster
Sequence 2:	NP_725784.1	Gene:	GstE9 / 246581	FlyBaseID:	FBgn0063491	Length:	221	Species:	Drosophila melanogaster

Alignment Length:	211	Identity:	75/211 - (35%)
Similarity:	114/211 - (54%)	Gaps:	12/211 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 SPRGSGCRTVIMVAKALGVKLNMKLLNTLEKDQLKPEFVKLNPQHTIPTLVDNGFSIWESRAIAV 70
            ||....|:   :...|||::...:|:|.|..:....||...|||||:|.|.|:|..||||.||..
  Fly    12 SPPVRACK---LTLDALGLQYEYRLVNLLAGEHKTKEFSLKNPQHTVPVLEDDGKFIWESHAICA 73

  Fly    71 YLVEKYGKDDTLFPKDPKKQALVNQRLYFDMGTLYDS-FAKYYYPLFH---TGKPGSDEDFKKIE 131
            |||.:|.|.|.|:|||..|:|||:|||:|:.|.|:.. ......|||:   |..|.|..|  .|.
  Fly    74 YLVRRYAKSDDLYPKDYFKRALVDQRLHFESGVLFQGCIRNIAIPLFYKNITEVPRSQID--AIY 136

  Fly   132 SSFEYLNIFLEGQNYVAGDHLTVADIAILSTVSTF-EIFDFDLNKYPNVARWYANAKKVTPGWEE 195
            .::::|..|:..|.|:.|..:|:||.:::|:||:. .:...|..:||.:..| .:.....|.::.
  Fly   137 EAYDFLEAFIGNQAYLCGPVITIADYSVVSSVSSLVGLAAIDAKRYPKLNGW-LDRMAAQPNYQS 200

  Fly   196 -NWKGAVELKGVFDAR 210
             |..||..|..:|.::
  Fly   201 LNGNGAQMLIDMFSSK 216

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstD5	NP_524914.3	GstA	1..184	CDD:223698	69/182 (38%)
		GST_N_Delta_Epsilon	1..74	CDD:239343	28/67 (42%)
		GST_C_Delta_Epsilon	88..204	CDD:198287	37/121 (31%)
GstE9	NP_725784.1	GstA	4..201	CDD:223698	70/194 (36%)
		GST_N_Delta_Epsilon	4..76	CDD:239343	27/66 (41%)
		GST_C_Delta_Epsilon	92..209	CDD:198287	37/119 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460227
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1231780at2759
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	10	9.900