DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstD5 and EEF1G

DIOPT Version :9

Sequence 1:	NP_524914.3	Gene:	GstD5 / 48338	FlyBaseID:	FBgn0010041	Length:	216	Species:	Drosophila melanogaster
Sequence 2:	NP_001395.1	Gene:	EEF1G / 1937	HGNCID:	3213	Length:	437	Species:	Homo sapiens

Alignment Length:	192	Identity:	44/192 - (22%)
Similarity:	87/192 - (45%)	Gaps:	29/192 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 PEFVKLNPQHTIPTLV-DNGFSIWESRAIAVYLVEKYGKDDTLFPKDPKKQALVNQRLYFDMGTL 104
            |||::..|...:|... |:||.::||.|||.|:     .::.|....|:..|.|.|.:.|....:
Human    47 PEFLRKFPAGKVPAFEGDDGFCVFESNAIAYYV-----SNEELRGSTPEAAAQVVQWVSFADSDI 106

  Fly   105 YDSFAKYYYP---LFHTGKPGSDEDFKKIESSFEYLNIFLEGQNYVAGDHLTVADIAILSTVSTF 166
            ....:.:.:|   :.|..|..::...:::......|:.:|:.:.::.|:.:|:|||.::.|:...
Human   107 VPPASTWVFPTLGIMHHNKQATENAKEEVRRILGLLDAYLKTRTFLVGERVTLADITVVCTLLWL 171

  Fly   167 --EIFDFDLNK-YPNVARWYANA------KKVTPGWEENWKGAVEL---KGVFDARQAAAKQ 216
              ::.:....: :||..||:...      :.|.        |.|:|   ...|||::.|..|
Human   172 YKQVLEPSFRQAFPNTNRWFLTCINQPQFRAVL--------GEVKLCEKMAQFDAKKFAETQ 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstD5	NP_524914.3	GstA	1..184	CDD:223698	35/149 (23%)
		GST_N_Delta_Epsilon	1..74	CDD:239343	14/33 (42%)
		GST_C_Delta_Epsilon	88..204	CDD:198287	23/130 (18%)
EEF1G	NP_001395.1	GST_N_EF1Bgamma	4..82	CDD:239342	14/39 (36%)
		GST_C_EF1Bgamma_like	91..213	CDD:198290	23/129 (18%)
		tolA	<212..>278	CDD:236545	5/14 (36%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	221..268		2/5 (40%)
		EF1G	277..381	CDD:395522
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810