DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstD5 and Gdap1

DIOPT Version :9

Sequence 1:	NP_524914.3	Gene:	GstD5 / 48338	FlyBaseID:	FBgn0010041	Length:	216	Species:	Drosophila melanogaster
Sequence 2:	NP_034397.1	Gene:	Gdap1 / 14545	MGIID:	1338002	Length:	358	Species:	Mus musculus

Alignment Length:	259	Identity:	43/259 - (16%)
Similarity:	81/259 - (31%)	Gaps:	100/259 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 VIMVAKALGVKLNMKLLNTLEKDQLKPEFVKLNPQHTIPTLVDNGFSIWESRAIAVYLVEKYGKD 79
            :::..|||..:.:...|...|.::  |.|::||....:|.||.....|.|:..|..||.:.:..:
Mouse    42 LVIAEKALKCEEHDVSLPLSEHNE--PWFMRLNSAGEVPVLVHGENIICEATQIIDYLEQTFLDE 104

  Fly    80 DTLFPKDPKKQALVNQRLYFDMGTLYDSFAKYY---------------------------YPLFH 117
            .|             .||..|.|::|....::|                           .|.:.
Mouse   105 RT-------------PRLMPDEGSMYYPRVQHYRELLDSLPMDAYTHGCILHPELTVDSMIPAYA 156

  Fly   118 TGK-----PGSDEDFKKI------------------------ESSFEYLNIFLE----------- 142
            |.:     ..::.:.||:                        ..:.:||...|:
Mouse   157 TTRIRSQIGNTESELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVKYLKKILDELEKVLDQVET 221

  Fly   143 -------------GQNYVAGDHLTVADIAILSTVSTFEIFDF-----DLNKYPNVARWYANAKK 188
                         .|.::.|:..|:||:::..|:...:...|     ...|.||:..:|....|
Mouse   222 ELQRRNEETPEEGNQPWLCGESFTLADVSLAVTLHRLKFLGFARRNWGHGKRPNLETYYERVLK 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstD5	NP_524914.3	GstA	1..184	CDD:223698	41/253 (16%)
		GST_N_Delta_Epsilon	1..74	CDD:239343	17/58 (29%)
		GST_C_Delta_Epsilon	88..204	CDD:198287	25/186 (13%)
Gdap1	NP_034397.1	GST_N_GDAP1	26..98	CDD:239350	16/57 (28%)
		GST_C_GDAP1	179..289	CDD:198336	15/107 (14%)
		Required for mitochondrial localization. /evidence=ECO:0000250	320..358
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844779
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840