Protein Alignment GstD5 and CLIC2

DIOPT Version :9

• Sequence 1: NP_524914.3
• Gene: GstD5 / 48338
• FlyBaseID: FBgn0010041
• Length: 216
• Species: Drosophila melanogaster
• Sequence 2: NP_001280.3
• Gene: CLIC2 / 1193
• HGNCID: 2063
• Length: 247
• Species: Homo sapiens
• Alignment Length: 215
• Identity: 53/215 - (24%)
• Similarity: 90/215 - (41%)
• Gaps: 68/215 - (31%)

  Fly    12 CRTVIMVAKALGVKLNMKLLNTLEKDQLKPEFVK-LNPQHTIPTLVDNGFSIWESRAIAVYLVEK 75
            |:.:.|:....|||.|:..::...    |||.:| |.|....|.||.|.....:...|..:|
Human    33 CQRLFMILWLKGVKFNVTTVDMTR----KPEELKDLAPGTNPPFLVYNKELKTDFIKIEEFL--- 90

  Fly    76 YGKDDTLFPK-----DPK-KQALVNQRLYFDMGTLYDSFAKYYYPLFHTGKPGSD-------EDF 127
               :.||.|.     .|| |::       ||:|.  :.|||:...:.:|.|..:.       ::|
Human    91 ---EQTLAPPRYPHLSPKYKES-------FDVGC--NLFAKFSAYIKNTQKEANKNFEKSLLKEF 143

  Fly   128 KKIESSFEYLN--------------------IFLEGQNYVAGDHLTVADIAILSTVSTFEIF--- 169
            |:::   :|||                    :||:      ||.||:||.::|..::..::.
Human   144 KRLD---DYLNTPLLDEIDPDSAEEPPVSRRLFLD------GDQLTLADCSLLPKLNIIKVAAKK 199

  Fly   170 --DFDL-NKYPNVARWYANA 186
              |||: .::..|.|:..||
Human   200 YRDFDIPAEFSGVWRYLHNA 219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstD5	NP_524914.3	GstA	1..184	CDD:223698	51/211 (24%)
		GST_N_Delta_Epsilon	1..74	CDD:239343	18/62 (29%)
		GST_C_Delta_Epsilon	88..204	CDD:198287	31/133 (23%)
CLIC2	NP_001280.3	Required for insertion into the membrane. /evidence=ECO:0000250	1..96		20/72 (28%)
		N-terminal	1..94		18/70 (26%)
		O-ClC	12..245	CDD:129941	53/215 (25%)
		Joint loop	95..106		2/10 (20%)
		C-terminal	107..247		30/131 (23%)
		Foot loop	151..171		1/19 (5%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154391
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930