DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstD4 and EEF1E1

DIOPT Version :9

Sequence 1:	NP_524913.1	Gene:	GstD4 / 48337	FlyBaseID:	FBgn0010040	Length:	215	Species:	Drosophila melanogaster
Sequence 2:	NP_004271.1	Gene:	EEF1E1 / 9521	HGNCID:	3212	Length:	174	Species:	Homo sapiens

Alignment Length:	191	Identity:	43/191 - (22%)
Similarity:	87/191 - (45%)	Gaps:	29/191 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 VAKALGLELNKKQLRITEGEHLKPEFLKLNPQHTIPTL-VDNGFAIWESRAIAVYLVEKYGKDDS 81
            :|.|..|.|.:|.|.:::|.....:     .:..||.| .:||.::.....||.:||::..| :.
Human     1 MAAAAELSLLEKSLGLSKGNKYSAQ-----GERQIPVLQTNNGPSLTGLTTIAAHLVKQANK-EY 59

  Fly    82 LFPNDPQKRALINQRLYFDMGTLHDSFMKYYYPFIRTGQLGNAENYKKVEAAFEFLDIFLEGQDY 146
            |..:..:::|::.|.|.:                 |..|:....:...:....:.|:.:||.:.|
Human    60 LLGSTAEEKAIVQQWLEY-----------------RVTQVDGHSSKNDIHTLLKDLNSYLEDKVY 107

  Fly   147 VAGSQLTVADIAILSSVSTFEVVEFDI---SKYPNVARWYANAKKITPGWDENWKGLLQMK 204
            :.|...|:|||.:...:..| :|:..:   .||.||:||:.:.:.. ||..::...::.:|
Human   108 LTGYNFTLADILLYYGLHRF-IVDLTVQEKEKYLNVSRWFCHIQHY-PGIRQHLSSVVFIK 166

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstD4	NP_524913.1	PRK10542	1..184	CDD:182533	40/169 (24%)
		GST_N_Delta_Epsilon	1..74	CDD:239343	15/56 (27%)
		GST_C_Delta_Epsilon	88..204	CDD:198287	24/118 (20%)
EEF1E1	NP_004271.1	N-terminal	2..56		16/58 (28%)
		Linker	57..63		2/6 (33%)
		C-terminal	64..152		22/105 (21%)
		GST_C_AIMP3	65..165	CDD:198338	24/118 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810