DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstD4 and CLIC3

DIOPT Version :9

Sequence 1:	NP_524913.1	Gene:	GstD4 / 48337	FlyBaseID:	FBgn0010040	Length:	215	Species:	Drosophila melanogaster
Sequence 2:	NP_004660.2	Gene:	CLIC3 / 9022	HGNCID:	2064	Length:	236	Species:	Homo sapiens

Alignment Length:	149	Identity:	32/149 - (21%)
Similarity:	56/149 - (37%)	Gaps:	32/149 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 PEFLK-LNPQHTIPTLVDNGFAIWESRAIAVYLVEKYGKDD--SLFPNDPQKRALINQRLYFDMG 102
            |:.|| ..|...:|.|:.:..|..::..|..:|.|..|..|  ||.|.            |.:..
Human    50 PDVLKDFAPGSQLPILLYDSDAKTDTLQIEDFLEETLGPPDFPSLAPR------------YRESN 102

  Fly   103 TLHDSFMKYYYPFIRTGQLGNAEN-YKKVEAAFEFLDIFLEG----------------QDYVAGS 150
            |..:.....:..||:.......|. |:::..|...||.:|..                :.::.|.
Human   103 TAGNDVFHKFSAFIKNPVPAQDEALYQQLLRALARLDSYLRAPLEHELAGEPQLRESRRRFLDGD 167

  Fly   151 QLTVADIAILSSVSTFEVV 169
            :||:||.::|..:...:.|
Human   168 RLTLADCSLLPKLHIVDTV 186

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstD4	NP_524913.1	PRK10542	1..184	CDD:182533	32/149 (21%)
		GST_N_Delta_Epsilon	1..74	CDD:239343	9/33 (27%)
		GST_C_Delta_Epsilon	88..204	CDD:198287	17/99 (17%)
CLIC3	NP_004660.2	Required for insertion into the membrane. /evidence=ECO:0000250	1..88		10/37 (27%)
CLIC3	NP_004660.2	PLN02817	5..229	CDD:330276	32/149 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154443
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930