DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstD4 and URE2

DIOPT Version :9

Sequence 1:	NP_524913.1	Gene:	GstD4 / 48337	FlyBaseID:	FBgn0010040	Length:	215	Species:	Drosophila melanogaster
Sequence 2:	NP_014170.1	Gene:	URE2 / 855492	SGDID:	S000005173	Length:	354	Species:	Saccharomyces cerevisiae

Alignment Length:	229	Identity:	59/229 - (25%)
Similarity:	103/229 - (44%)	Gaps:	59/229 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 YSPRS--SGSRTIIMVAKALGLELNKKQLRITEGEHLKPEFLKLNPQHTIPTLVDNG---FAIWE 64
            :|.||  :|.:..|:::: ||...|...|....|||..|||:.:||...:|.|:|:|   .:|||
Yeast   117 FSHRSAPNGFKVAIVLSE-LGFHYNTIFLDFNLGEHRAPEFVSVNPNARVPALIDHGMDNLSIWE 180

  Fly    65 SRAIAVYLVEKYGKDDS---LFPNDPQKRALINQRLYFDMG--------TLHDSFMKYYYPFIRT 118
            |.||.::||.||.|:..   |:.:|...::.||..|:|...        .||   .:|::    :
Yeast   181 SGAILLHLVNKYYKETGNPLLWSDDLADQSQINAWLFFQTSGHAPMIGQALH---FRYFH----S 238

  Fly   119 GQLGNA-ENY----------------KKVEAAFEFLDI-----------------FLEGQDYVAG 149
            .::.:| |.|                ::.||....||.                 |.:...::.|
Yeast   239 QKIASAVERYTDEVRRVYGVVEMALAERREALVMELDTENAAAYSAGTTPMSQSRFFDYPVWLVG 303

  Fly   150 SQLTVADIAILSSVSTFEVVEFDIS-KYPNVARW 182
            .:||:||:|.:...:..:.:..:|. ::|.|.:|
Yeast   304 DKLTIADLAFVPWNNVVDRIGINIKIEFPEVYKW 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstD4	NP_524913.1	PRK10542	1..184	CDD:182533	59/229 (26%)
		GST_N_Delta_Epsilon	1..74	CDD:239343	28/73 (38%)
		GST_C_Delta_Epsilon	88..204	CDD:198287	25/138 (18%)
URE2	NP_014170.1	GST_N_Ure2p_like	114..194	CDD:239346	31/77 (40%)
URE2	NP_014170.1	GST_C_Ure2p	208..350	CDD:198326	25/137 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	52	1.000	Domainoid score	I2827
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	68	1.000	Inparanoid score	I1709
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
TreeFam	1	0.960	-	-
	9	8.720