DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstD4 and Clic4

DIOPT Version :9

Sequence 1:	NP_524913.1	Gene:	GstD4 / 48337	FlyBaseID:	FBgn0010040	Length:	215	Species:	Drosophila melanogaster
Sequence 2:	NP_114006.1	Gene:	Clic4 / 83718	RGDID:	61857	Length:	253	Species:	Rattus norvegicus

Alignment Length:	159	Identity:	38/159 - (23%)
Similarity:	64/159 - (40%)	Gaps:	49/159 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 PEFLKLNPQHTIPTLVDNGFAIWESRAIAVYLVEK---YGKDDSLFPNDPQKRALIN--QRLYFD 100
            |::|||:|:|.            ||....:.:..|   |.|:.....|:..:|.|:.  |:|
  Rat   102 PKYLKLSPKHP------------ESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQKL--- 151

  Fly   101 MGTLHDSFMKYYYPFIRTGQL--GNAENYKKVEAAFEFLDIFLEGQDYVAGSQLTVADIAILSSV 163
                 |.::....|    |::  .:.|:.|  .:...|||          |.::|:||..:|..:
  Rat   152 -----DEYLNSPLP----GEIDENSMEDIK--SSTRRFLD----------GDEMTLADCNLLPKL 195

  Fly   164 STFEVV-----EFDISK-YPNVARWYANA 186
            ...:||     .|||.| ...:.|:..||
  Rat   196 HIVKVVAKKYRNFDIPKGMTGIWRYLTNA 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstD4	NP_524913.1	PRK10542	1..184	CDD:182533	36/155 (23%)
		GST_N_Delta_Epsilon	1..74	CDD:239343	8/32 (25%)
		GST_C_Delta_Epsilon	88..204	CDD:198287	26/109 (24%)
Clic4	NP_114006.1	Required for insertion into the membrane. /evidence=ECO:0000250	2..101
		GST_N_CLIC	14..104	CDD:239359	1/1 (100%)
		O-ClC	17..252	CDD:129941	38/159 (24%)
		GST_C_family	111..251	CDD:295467	33/150 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347845
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930