DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstD4 and GSTZ1

DIOPT Version :9

Sequence 1:	NP_524913.1	Gene:	GstD4 / 48337	FlyBaseID:	FBgn0010040	Length:	215	Species:	Drosophila melanogaster
Sequence 2:	NP_001350632.1	Gene:	GSTZ1 / 2954	HGNCID:	4643	Length:	217	Species:	Homo sapiens

Alignment Length:	186	Identity:	51/186 - (27%)
Similarity:	87/186 - (46%)	Gaps:	24/186 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 RSSGSRTIIMVAKALGLELNKKQLRITE--GEHLKPEFLKLNPQHTIPTLVDNGFAIWESRAIAV 70
            |||.|..:.:.....|::.....:.:.:  |:....:|..|||...:|||..:|..|.:|.||..
Human    14 RSSCSWRVRIALALKGIDYETVPINLIKDGGQQFSKDFQALNPMKQVPTLKIDGITIHQSLAIIE 78

  Fly    71 YLVEKYGKDDSLFPNDPQKRALINQRLYFDM--GTLHD----SFMKYYYPFIRTG---QLGNAEN 126
            || |:......|.|.||:|||.:  |:..|:  |.:..    |.:|      :.|   ||..|:|
Human    79 YL-EEMRPTPRLLPQDPKKRASV--RMISDLIAGGIQPLQNLSVLK------QVGEEMQLTWAQN 134

  Fly   127 YKKVEAAFEFLDIFLEGQD--YVAGSQLTVADIAILSSVSTFEVVEFDISKYPNVA 180
              .:...|..|:..|:...  |..|.::|:||:.::..|:..|..:.|::.||.::
Human   135 --AITCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAERFKVDLTPYPTIS 188

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstD4	NP_524913.1	PRK10542	1..184	CDD:182533	51/186 (27%)
		GST_N_Delta_Epsilon	1..74	CDD:239343	20/67 (30%)
		GST_C_Delta_Epsilon	88..204	CDD:198287	26/104 (25%)
GSTZ1	NP_001350632.1	maiA	8..212	CDD:273527	51/186 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810