Protein Alignment GstD3 and AIMP2

DIOPT Version :10

• Sequence 1: NP_788656.1
• Gene: GstD3 / 48336
• FlyBaseID: FBgn0010039
• Length: 199
• Species: Drosophila melanogaster
• Sequence 2: NP_006294.2
• Gene: AIMP2 / 7965
• HGNCID: 20609
• Length: 320
• Species: Homo sapiens
• Alignment Length: 187
• Identity: 40/187 - (21%)
• Similarity: 64/187 - (34%)
• Gaps: 66/187 - (35%)

  Fly    16 NTLK--GEQMNPDFIKINPQHSIPTLVDNGFT-IWESRAILVYLVEKYGKDDALYPKDIQKQAVI 77
            |.||  |||.     |..|:.....    ||| ||::                 .||...|
Human   164 NLLKCFGEQN-----KKQPRQDYQL----GFTLIWKN-----------------VPKTQMK---- 198

  Fly    78 NQRLYFDMALMYP-----TLANYYYKAFTTGQFGS-------------------EEDYKKVQETF 118
                 |.:..|.|     .:|.:.:..|  ||..:                   |...|:....|
Human   199 -----FSIQTMCPIEGEGNIARFLFSLF--GQKHNAVNATLIDSWVDIAIFQLKEGSSKEKAAVF 256

  Fly   119 DFLNTFLEGQDYVAGDQYTVADIAILANVSNFDVVGFDISKYPNVARWYDHVKKITP 175
            ..:|:.|....::||::.||||:.:.:.:.  .:.|..::...||.||....:.:.|
Human   257 RSMNSALGKSPWLAGNELTVADVVLWSVLQ--QIGGCSVTVPANVQRWMRSCENLAP 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstD3	NP_788656.1	GST_N_Delta_Epsilon	<1..58	CDD:239343	13/44 (30%)
		GST_C_Delta_Epsilon	72..188	CDD:198287	25/128 (20%)
AIMP2	NP_006294.2	AIMP2_LysRS_bd	1..44	CDD:465269
		Interaction with PRKN. /evidence=ECO:0000269|PubMed:16135753	82..162
		Thioredoxin_16	117..208	CDD:436585	19/78 (24%)
		Interaction with TP53. /evidence=ECO:0000269|PubMed:18695251	162..225		23/97 (24%)
		GST_C_AIMP2	214..309	CDD:198309	20/98 (20%)