DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstD3 and GDAP1L1

DIOPT Version :9

Sequence 1:	NP_788656.1	Gene:	GstD3 / 48336	FlyBaseID:	FBgn0010039	Length:	199	Species:	Drosophila melanogaster
Sequence 2:	NP_001243666.1	Gene:	GDAP1L1 / 78997	HGNCID:	4213	Length:	386	Species:	Homo sapiens

Alignment Length:	185	Identity:	35/185 - (18%)
Similarity:	67/185 - (36%)	Gaps:	62/185 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVGKALGLEFNKKIINTLKGEQMNPDFIKIN----PQHSIPTLVDNGFTIWESRAILVYLVEKYG 61
            |:.|....|..:.:.|.      ..|.:|::    ||.|.|.|.       :.:.::..::|
Human   191 MIPKYATAEIRRHLANA------TTDLMKLDHEEEPQLSEPYLS-------KQKKLMAKILE--- 239

  Fly    62 KDDALYPKDIQKQAVINQRLYFDMALMYPTLANYYYKAFTTGQFGSEEDYKKVQETFDFLNTFLE 126
            .||..|.|.|..:.                       |....|..:|.:.:|::.         |
Human   240 HDDVSYLKKILGEL-----------------------AMVLDQIEAELEKRKLEN---------E 272

  Fly   127 GQD---YVAGDQYTVADIAILANVSNFDVVGFDISKY------PNVARWYDHVKK 172
            ||.   ::.|..:|:||:.:.|.:.....:|.. .||      ||:..:::.|::
Human   273 GQKCELWLCGCAFTLADVLLGATLHRLKFLGLS-KKYWEDGSRPNLQSFFERVQR 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstD3	NP_788656.1	GST_N_Delta_Epsilon	<1..58	CDD:239343	11/60 (18%)
		GstA	6..173	CDD:223698	33/180 (18%)
		GST_C_Delta_Epsilon	72..188	CDD:198287	18/110 (16%)
GDAP1L1	NP_001243666.1	GstA	47..333	CDD:223698	35/185 (19%)
		GST_N_GDAP1	47..119	CDD:239350
		GST_C_GDAP1L1	220..330	CDD:198335	29/150 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154480
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1283865at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.850