DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstD3 and gst2

DIOPT Version :9

Sequence 1:	NP_788656.1	Gene:	GstD3 / 48336	FlyBaseID:	FBgn0010039	Length:	199	Species:	Drosophila melanogaster
Sequence 2:	NP_588517.1	Gene:	gst2 / 2539601	PomBaseID:	SPCC965.07c	Length:	230	Species:	Schizosaccharomyces pombe

Alignment Length:	223	Identity:	55/223 - (24%)
Similarity:	91/223 - (40%)	Gaps:	48/223 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 KALGLEFNKKIINTLKGEQMNPDFIKINPQHSIPTLVD---NGFTIWESRAILVYLVEKYGKDDA 65
            |.|.|.:.:...:..||||...:.:.:||...:|||||   |.:|||||.|||:||.:||..|..
pombe    23 KELNLSYEQIFYDFQKGEQKCKEHLALNPNGRVPTLVDHKNNDYTIWESDAILIYLADKYDTDRK 87

  Fly    66 LYPKDIQKQAVINQRLYFDMALMYPTLANYYYKAFTTGQFGSEEDY-----------------KK 113
            :             .|.||....|..:...:::|...|....:..:                 .:
pombe    88 I-------------SLSFDDPEYYKLIQYLFFQASGQGVIWGQAGWFNFFHHEPVVSAVTRYRNE 139

  Fly   114 VQETFDFLNTFLEGQDYVAGDQYTVADIAILANVSNFDVVG-FDISKY------PNVARWYDHVK 171
            ::.....|...|:.:||:..::||:||::.:.  .|:::.| |...|:      |.:    |..|
pombe   140 IKRVLGVLEDILKDRDYLVANKYTIADLSFIP--WNYNLGGLFGEGKFSFKEEVPQL----DFEK 198

  Fly   172 KITP--GWEENWAGALDVKKRIEEKQNA 197
            :...  .|.:.......||...||...|
pombe   199 EFPKAYAWNQRLLARPAVKATFEELAKA 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstD3	NP_788656.1	GST_N_Delta_Epsilon	<1..58	CDD:239343	25/56 (45%)
		GstA	6..173	CDD:223698	48/193 (25%)
		GST_C_Delta_Epsilon	72..188	CDD:198287	22/141 (16%)
gst2	NP_588517.1	GST_N_Ure2p_like	4..84	CDD:239346	27/60 (45%)
		GstA	5..226	CDD:223698	54/221 (24%)
		GST_C_Ure2p	96..219	CDD:198326	21/128 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	54	1.000	Domainoid score	I3221
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	80	1.000	Inparanoid score	I1854
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm9258
orthoMCL	1	0.900	-	-		OOG6_100130
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R16332
SonicParanoid	1	1.000	-	-		X30
TreeFam	1	0.960	-	-
	11	10.750